# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5145660 | B | Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK293 cell membrane by competitive inhibition based analysis | Homo sapiens | 49 | ALA5143585 | cell membrane format | Scientific Literature | |
2. | ALA5145663 | B | Displacement of [3H]-SCH23390 from human D1 receptor expressed in HEK293 cell membrane at 10 uM by competitive inhibition based analysis | Homo sapiens | 54 | ALA5143585 | cell membrane format | Scientific Literature | |
3. | ALA5145664 | B | Displacement of [3H]N-methylspiperone from human D2 receptor expressed in HEK293 cell membrane at 10 uM by competitive inhibition based analysis | Homo sapiens | 54 | ALA5143585 | cell membrane format | Scientific Literature | |
4. | ALA5145665 | B | Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membrane at 10 uM by competitive inhibition based analysis | Homo sapiens | 54 | ALA5143585 | cell membrane format | Scientific Literature | |
5. | ALA5145667 | B | Displacement of [3H]-SCH23390 from human D5 receptor expressed in HEK293 cell membrane at 10 uM by competitive inhibition based analysis | Homo sapiens | 54 | ALA5143585 | cell membrane format | Scientific Literature | |
6. | ALA5145669 | A | Intrinsic clearance in human liver microsomes | Homo sapiens | 23 | ALA5143585 | microsome format | Scientific Literature | |
7. | ALA5145670 | A | Intrinsic clearance in mouse liver microsomes | Mus musculus | 23 | ALA5143585 | microsome format | Scientific Literature | |
8. | ALA5145671 | A | Protein binding in human plasma assessed as unbound fraction | Homo sapiens | 23 | ALA5143585 | cell-free format | Scientific Literature | |
9. | ALA5145672 | A | Protein binding in mouse plasma assessed as unbound fraction | Mus musculus | 22 | ALA5143585 | cell-free format | Scientific Literature | |
10. | ALA5145674 | A | Clearance in rat at 0.25 mg/kg, iv measured for 24 hrs | Rattus norvegicus | 8 | ALA5143585 | organism-based format | Scientific Literature | |
11. | ALA5145675 | A | Half-life in rat at 0.25 mg/kg, iv measured for 24 hrs | Rattus norvegicus | 8 | ALA5143585 | organism-based format | Scientific Literature | |
12. | ALA5145676 | A | Initial plasma concentration in rat at 0.25 mg/kg, iv | Rattus norvegicus | 8 | ALA5143585 | organism-based format | Scientific Literature | |
13. | ALA5145677 | A | Volume of distribution at steady state in rat at 0.25 mg/kg, iv measured for 24 hrs | Rattus norvegicus | 8 | ALA5143585 | organism-based format | Scientific Literature | |
14. | ALA5145678 | A | AUC in rat at 0.25 mg/kg, iv measured for 24 hrs | Rattus norvegicus | 8 | ALA5143585 | organism-based format | Scientific Literature | |
15. | ALA5145679 | A | Plasma concentration in rat at 0.25 mg/kg, iv measured on day 2 at 0.25 hrs post-dose | Rattus norvegicus | 8 | ALA5143585 | organism-based format | Scientific Literature | |
16. | ALA5145680 | A | Drug uptake in rat brain at 0.25 mg/kg, iv measured on day 2 at 0.25 hrs post-dose | Rattus norvegicus | 8 | ALA5143585 | organism-based format | Scientific Literature | |
17. | ALA5145681 | A | Ratio of drug level in rat brain to plasma at 0.25 mg/kg, iv measured on day 2 at 0.25 hrs post-dose | Rattus norvegicus | 8 | ALA5143585 | organism-based format | Scientific Literature | |
18. | ALA5250270 | B | Displacement of [3H] Pentazocine from sigma 1 receptor in HEK293 cell membrane | Homo sapiens | 65 | ALA5247621 | cell membrane format | Scientific Literature | |
19. | ALA5250271 | B | Displacement of [3H]N-methylspiperone from D4 receptor in HEK293 cell membrane | Homo sapiens | 51 | ALA5247621 | cell membrane format | Scientific Literature | |
20. | ALA5250275 | B | Displacement of [3H]DTG from sigma-2 receptor in HEK293 cell membrane assessed as inhibition constant | Homo sapiens | 20 | ALA5247621 | cell membrane format | Scientific Literature |