| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5217405 | B | Binding affinity to human G-quadruplex telomeric DNA F21T (5'-duplex FAM-GGGTTAGGGTTAGGGTTAGGG-TAM-3') assessed as stabilization by measuring change in melting temperature at 5 uM by FRET melting assay | Homo sapiens | 17 | nucleic acid format | Scientific Literature | ||
| 2. | ALA5217406 | B | Binding affinity to human G-quadruplex telomeric DNA F21CTAT (5'-duplex FAM-GGGCTAGGGCTAGGGCTAGGG-TAM-3') assessed as stabilization by measuring change in melting temperature at 5 uM by FRET melting assay | Homo sapiens | 17 | nucleic acid format | Scientific Literature | ||
| 3. | ALA5217407 | B | Binding affinity to human G-quadruplex telomeric DNA F25CebT (5'-duplex FAM-AGGGTGGGTGTAAGTGTGGGTGGGT-TAM-3') assessed as stabilization by measuring change in melting temperature at 5 uM by FRET melting assay | Homo sapiens | 17 | nucleic acid format | Scientific Literature | ||
| 4. | ALA5217408 | B | Binding affinity to G-quadruplex telomeric DNA FdxT (5'-duplex FAM-TATAGCTAT-PEG-TATAGCTATA-TAM-3') assessed as stabilization by measuring change in melting temperature at 5 uM by FRET melting assay | Not specified | 17 | nucleic acid format | Scientific Literature | ||
| 5. | ALA5217421 | F | Antiproliferative activity against human A549 cells assessed as cell viability at 10 uM after 48 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 6. | ALA5217422 | F | Antiproliferative activity against human NCI-H1299 cells assessed as cell viability at 10 uM after 48 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 7. | ALA5217423 | T | Cytotoxicity against human NHDF cells assessed as cell viability at 10 uM after 48 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!