| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5216090 | B | Inhibition of human KDM6B preincubated for 15 mins followed by substrate addition and measured after 5 mins using H3(21-44)K27Me3-GK-biotin peptide as substrate by AlphaScreen-based assay | Homo sapiens | 12 | ALA5214918 | single protein format | Scientific Literature | |
| 2. | ALA5216101 | B | Inhibition of recombinant full length N-terminal hexahistidine-tagged human FTO demethylation activity expressed in Escherichia coli BL21 (DE3) incubated for 1 hrs using m3T nucleoside as substrate by LCMS-based assay | Homo sapiens | 6 | ALA5214918 | assay format | Scientific Literature | |
| 3. | ALA5216102 | B | Inhibition of recombinant full length N-terminal hexahistidine-tagged human FTO demethylation activity expressed in Escherichia coli BL21 (DE3) incubated for 30 mins using 5-mer ssRNA oligonucleotide [GG(m6A)CU] as substrate by LCMS-based assay | Homo sapiens | 12 | ALA5214918 | assay format | Scientific Literature | |
| 4. | ALA5216106 | B | Inhibition of human KDM3A preincubated for 15 mins followed by substrate addition and measured after 5 mins using H3(1-21)K9Me2-GGK-Biotin peptide as substrate by AlphaScreen-based assay | Homo sapiens | 12 | ALA5214918 | single protein format | Scientific Literature | |
| 5. | ALA5216107 | B | Inhibition of human KDM4C preincubated for 15 mins followed by substrate addition and measured after 15 mins using H3(1-21)K9Me3-GGK-Biotin peptide as substrate by AlphaScreen-based assay | Homo sapiens | 12 | ALA5214918 | single protein format | Scientific Literature | |
| 6. | ALA5216108 | B | Inhibition of human KDM5B preincubated for 15 mins followed by substrate addition and measured after 20 mins using H3(1-21)K4Me3-GGK-Biotin peptide as substrate by AlphaScreen-based assay | Homo sapiens | 12 | ALA5214918 | single protein format | Scientific Literature | |
| 7. | ALA5216109 | B | Inhibition of human KDM2A preincubated for 15 mins followed by substrate addition and measured after 30 mins using Biotin-H3(28-48)K36Me2 peptide as substrate by AlphaScreen-based assay | Homo sapiens | 12 | ALA5214918 | single protein format | Scientific Literature | |
| 8. | ALA5216110 | B | Binding affinity to recombinant full length N-terminal hexahistidine-tagged human FTO expressed in Escherichia coli BL21 by competition-based NMR binding assay | Homo sapiens | 4 | ALA5214918 | assay format | Scientific Literature |
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