# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5216717 | F | Antagonist activity at human muscarinic M4 receptor | Homo sapiens | 5 | assay format | Scientific Literature | ||
2. | ALA5216718 | F | Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
3. | ALA5216719 | F | Antagonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as minimal acetylcholine response by calcium mobilisation assay relative to control | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
4. | ALA5216720 | A | Intrinsic clearance in human | Homo sapiens | 18 | assay format | Scientific Literature | ||
5. | ALA5216721 | A | Intrinsic clearance in rat | Rattus norvegicus | 18 | assay format | Scientific Literature | ||
6. | ALA5216722 | F | Antagonist activity at rat muscarinic M5 receptor | Rattus norvegicus | 3 | assay format | Scientific Literature | ||
7. | ALA5216723 | F | Antagonist activity at rat muscarinic M5 receptor assessed as minimal acetylcholine response relative to control | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
8. | ALA5216725 | F | Antagonist activity at human muscarinic M1 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA5216726 | F | Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as minimal acetylcholine response by calcium mobilisation assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA5216727 | A | Unbound fraction in rat plasma | Rattus norvegicus | 4 | cell-free format | Scientific Literature | ||
11. | ALA5216728 | A | Unbound fraction in human plasma | Homo sapiens | 4 | cell-free format | Scientific Literature | ||
12. | ALA5216729 | A | Unbound fraction in rat brain | Rattus norvegicus | 4 | tissue-based format | Scientific Literature | ||
13. | ALA5216733 | A | Efflux ratio of permeability in MDCK-MDR1 cells expressing human P-glycoprotein | Canis lupus familiaris | 2 | cell-based format | Scientific Literature | ||
14. | ALA5216734 | A | Apparent permeability in MDCK-MDR1 cells | Canis lupus familiaris | 2 | cell-based format | Scientific Literature |