| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5217405 | B | Binding affinity to human G-quadruplex telomeric DNA F21T (5'-duplex FAM-GGGTTAGGGTTAGGGTTAGGG-TAM-3') assessed as stabilization by measuring change in melting temperature at 5 uM by FRET melting assay | Homo sapiens | 17 | nucleic acid format | Scientific Literature | ||
| 2. | ALA5217406 | B | Binding affinity to human G-quadruplex telomeric DNA F21CTAT (5'-duplex FAM-GGGCTAGGGCTAGGGCTAGGG-TAM-3') assessed as stabilization by measuring change in melting temperature at 5 uM by FRET melting assay | Homo sapiens | 17 | nucleic acid format | Scientific Literature | ||
| 3. | ALA5217407 | B | Binding affinity to human G-quadruplex telomeric DNA F25CebT (5'-duplex FAM-AGGGTGGGTGTAAGTGTGGGTGGGT-TAM-3') assessed as stabilization by measuring change in melting temperature at 5 uM by FRET melting assay | Homo sapiens | 17 | nucleic acid format | Scientific Literature | ||
| 4. | ALA5217408 | B | Binding affinity to G-quadruplex telomeric DNA FdxT (5'-duplex FAM-TATAGCTAT-PEG-TATAGCTATA-TAM-3') assessed as stabilization by measuring change in melting temperature at 5 uM by FRET melting assay | Not specified | 17 | nucleic acid format | Scientific Literature | ||
| 5. | ALA5217409 | B | Binding affinity to G-quadruplex telomeric DNA 22AG (5'-duplex AGGGTTAGGGTTAGGGTTAGGG-3') (unknown origin) assessed as stabilization by measuring change in melting temperature at 0.5 M by circular dichroism (CD) spectroscopy | Not specified | 3 | nucleic acid format | Scientific Literature | ||
| 6. | ALA5217410 | B | Binding affinity to G-quadruplex telomeric DNA 22AG (5'-duplex AGGGTTAGGGTTAGGGTTAGGG-3') (unknown origin) assessed as stabilization by measuring change in melting temperature at 1 M by circular dichroism (CD) spectroscopy | Not specified | 3 | nucleic acid format | Scientific Literature | ||
| 7. | ALA5217411 | B | Binding affinity to G-quadruplex telomeric DNA 22AG (5'-duplex AGGGTTAGGGTTAGGGTTAGGG-3') (unknown origin) assessed as stabilization by measuring change in melting temperature at 3 M by circular dichroism (CD) spectroscopy | Not specified | 3 | nucleic acid format | Scientific Literature | ||
| 8. | ALA5217412 | B | Binding affinity to G-quadruplex telomeric DNA 22AG (5'-duplex AGGGTTAGGGTTAGGGTTAGGG-3') (unknown origin) assessed as stabilization by measuring change in melting temperature at 5 M by circular dichroism (CD) spectroscopy | Not specified | 3 | nucleic acid format | Scientific Literature | ||
| 9. | ALA5217413 | B | Binding affinity to G-quadruplex telomeric DNA 22CTA (5'-duplex AGGGCTAGGGCTAGGGCTAGGG-3') (unknown origin) assessed as stabilization by measuring change in melting temperature at 0.5 M by circular dichroism (CD) spectroscopy | Not specified | 3 | nucleic acid format | Scientific Literature | ||
| 10. | ALA5217414 | B | Binding affinity to G-quadruplex telomeric DNA 22CTA (5'-duplex AGGGCTAGGGCTAGGGCTAGGG-3') (unknown origin) assessed as stabilization by measuring change in melting temperature at 1 M by circular dichroism (CD) spectroscopy | Not specified | 3 | nucleic acid format | Scientific Literature | ||
| 11. | ALA5217415 | B | Binding affinity to G-quadruplex telomeric DNA 22CTA (5'-duplex AGGGCTAGGGCTAGGGCTAGGG-3') (unknown origin) assessed as stabilization by measuring change in melting temperature at 3 M by circular dichroism (CD) spectroscopy | Not specified | 3 | nucleic acid format | Scientific Literature | ||
| 12. | ALA5217416 | B | Binding affinity to G-quadruplex telomeric DNA 22CTA (5'-duplex AGGGCTAGGGCTAGGGCTAGGG-3') (unknown origin) assessed as stabilization by measuring change in melting temperature at 5 M by circular dichroism (CD) spectroscopy | Not specified | 3 | nucleic acid format | Scientific Literature | ||
| 13. | ALA5217417 | B | Binding affinity to G-quadruplex telomeric DNA 26ceb (5'-duplex AAGGGTGGGTGTAAGTGTGGGTGGGT-3') (unknown origin) assessed as stabilization by measuring change in melting temperature at 0.5 M by circular dichroism (CD) spectroscopy | Not specified | 3 | nucleic acid format | Scientific Literature | ||
| 14. | ALA5217418 | B | Binding affinity to G-quadruplex telomeric DNA 26ceb (5'-duplex AAGGGTGGGTGTAAGTGTGGGTGGGT-3') (unknown origin) assessed as stabilization by measuring change in melting temperature at 1 M by circular dichroism (CD) spectroscopy | Not specified | 3 | nucleic acid format | Scientific Literature | ||
| 15. | ALA5217419 | B | Binding affinity to G-quadruplex telomeric DNA 26ceb (5'-duplex AAGGGTGGGTGTAAGTGTGGGTGGGT-3') (unknown origin) assessed as stabilization by measuring change in melting temperature at 3 M by circular dichroism (CD) spectroscopy | Not specified | 3 | nucleic acid format | Scientific Literature | ||
| 16. | ALA5217420 | B | Binding affinity to G-quadruplex telomeric DNA 26ceb (5'-duplex AAGGGTGGGTGTAAGTGTGGGTGGGT-3') (unknown origin) assessed as stabilization by measuring change in melting temperature at 5 M by circular dichroism (CD) spectroscopy | Not specified | 3 | nucleic acid format | Scientific Literature | ||
| 17. | ALA5217421 | F | Antiproliferative activity against human A549 cells assessed as cell viability at 10 uM after 48 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 18. | ALA5217422 | F | Antiproliferative activity against human NCI-H1299 cells assessed as cell viability at 10 uM after 48 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 19. | ALA5217423 | T | Cytotoxicity against human NHDF cells assessed as cell viability at 10 uM after 48 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature |
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