# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5218029 | B | Inhibition of 15-PGDH (unknown origin) using NAD as substrate measured for 3.5 mins | Homo sapiens | 55 | ALA5214995 | single protein format | Scientific Literature | |
2. | ALA5218030 | P | Aqueous solubility of the compound under shaking condition by LC-MS/MS analysis | 5 | ALA5214995 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA5218031 | A | Metabolic stability in ICR/CD-1 mouse liver S9 fraction assessed as half life at 2 uM preincubated for 5 mins followed by NADPH regenerating system addition by LC-MS/MS analysis | Mus musculus | 5 | ALA5214995 | subcellular format | Scientific Literature | |
4. | ALA5218032 | A | Cmax in CD-1 mouse at 10 mg/kg,ip measured upto 1440 mins by LC-MS/MS analysis | Mus musculus | 3 | ALA5214995 | organism-based format | Scientific Literature | |
5. | ALA5218033 | A | AUC in CD-1 mouse at 10 mg/kg,ip measured upto 1440 mins by LC-MS/MS analysis | Mus musculus | 3 | ALA5214995 | organism-based format | Scientific Literature | |
6. | ALA5218042 | B | Induction of PGE2 in IL-1beta stimulated human A549 cells at 4 nM incubated for 24 hrs by ELISA assay | Homo sapiens | 2 | ALA5214995 | cell-based format | Scientific Literature | |
7. | ALA5218043 | F | Invivo activation of PGE2 in C57BL/6J mouse colon tissue assessed as increase in PGE2 level at 5 mg/kg,ip measured after 3 hrs by ELISA | Mus musculus | 2 | ALA5214995 | organism-based format | Scientific Literature | |
8. | ALA5218044 | F | Invivo activation of PGE2 in C57BL/6J mouse lung tissue assessed as increase in PGE2 level at 5 mg/kg,ip measured after 3 hrs by ELISA | Mus musculus | 2 | ALA5214995 | organism-based format | Scientific Literature |