| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5217271 | B | Activation of HIF-alpha transcriptional activity in human SK-N-BE(2)-C expressing HRE-NLuc reporter system assessed as compound concentration require for 5 fold increase in NLuc luciferase activity incubated for 24 hrs by Nano-Glo luciferase assay | Homo sapiens | 22 | ALA5214962 | cell-based format | Scientific Literature | |
| 2. | ALA5217272 | T | Cytotoxicity against human SK-N-BE(2)-C expressing HRE-NLuc reporter system assessed as reduction in cell viability incubated for 24 hrs by CCK-8 assay | Homo sapiens | 22 | ALA5214962 | cell-based format | Scientific Literature | |
| 3. | ALA5217273 | B | Induction of HIF-1alpha stabilization in human Hep3B cells assessed as HIF-1alpha level at 1 to 100 uM incubated for 24 hrs by immunoblot analysis | Homo sapiens | 3 | ALA5214962 | cell-based format | Scientific Literature | |
| 4. | ALA5217274 | B | Induction of HIF-2alpha stabilization in human Hep3B cells assessed as HIF-1alpha level at 1 to 100 uM incubated for 24 hrs by immunoblot analysis | Homo sapiens | 3 | ALA5214962 | cell-based format | Scientific Literature | |
| 5. | ALA5217275 | B | Induction of HIF-1alpha stabilization in human Hep3B cells assessed as HIF-1alpha level at 16 to 1000 nM incubated for 24 hrs by immunoblot analysis | Homo sapiens | 1 | ALA5214962 | cell-based format | Scientific Literature | |
| 6. | ALA5217276 | B | Induction of HIF-2alpha stabilization in human Hep3B cells assessed as HIF-1alpha level at 16 to 1000 nM incubated for 24 hrs by immunoblot analysis | Homo sapiens | 1 | ALA5214962 | cell-based format | Scientific Literature | |
| 7. | ALA5217277 | B | Activation of HIF dependent pathway in human Hep3B cells assessed as increase in CA9 mRNA expression level at 10 to 100 uM incubated for 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA5214962 | cell-based format | Scientific Literature | |
| 8. | ALA5217278 | B | Activation of HIF dependent pathway in human Hep3B cells assessed as increase in EPO mRNA expression level at 10 to 100 uM incubated for 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA5214962 | cell-based format | Scientific Literature |
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