# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5216896 | Functional | Reversible inhibition of MAO-B in mouse brain assessed as MAO-B activity recovered at 21 hrs at 10 mg/kg when administered as single dose | Mus musculus | 1 | ALA5214946 | organism-based format | Scientific Literature | |
2. | ALA5216897 | Functional | Reversible inhibition of MAO-B in mouse brain assessed as MAO-B activity recovered after 4 hrs at 10 mg/kg when administered as single dose | Mus musculus | 1 | ALA5214946 | organism-based format | Scientific Literature | |
3. | ALA5216900 | Binding | Specificity index, ratio of IC50 for inhibition of human MAO-A to IC50 for inhibition of MAO-B | Homo sapiens | 19 | ALA5214946 | assay format | Scientific Literature | |
4. | ALA5216901 | Functional | In vivo inhibition of MAO-B in resperine-induced mouse assessed as decrease in MAO-B activity in brain at 10 mg/kg | Mus musculus | 4 | ALA5214946 | organism-based format | Scientific Literature | |
5. | ALA5216902 | Binding | Inhibition of recombinant human MAO-B | Homo sapiens | 25 | ALA5214946 | single protein format | Scientific Literature | |
6. | ALA5216903 | Binding | Inhibition of human MAO-A | Homo sapiens | 19 | ALA5214946 | single protein format | Scientific Literature | |
7. | ALA5216904 | Toxicity | Cytotoxicity against human SH-SY5Y cells at 1 to 80 uM by MTT assay | Homo sapiens | 6 | ALA5214946 | cell-based format | Scientific Literature |