# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5216985 | B | Inhibition of norepinephrine transporter (unknown origin) assessed as inhibition of norepinephrine reuptake | Homo sapiens | 5 | ALA5214950 | single protein format | Scientific Literature | |
2. | ALA5216986 | B | Inhibition of dopamine transporter (unknown origin) assessed as inhibition of dopamine reuptake | Homo sapiens | 5 | ALA5214950 | single protein format | Scientific Literature | |
3. | ALA5216987 | B | Binding affinity to recombinant CYP2B6 (unknown origin) assessed as spectral dissociation constant-1 | Homo sapiens | 5 | ALA5214950 | single protein format | Scientific Literature | |
4. | ALA5216988 | B | Binding affinity to recombinant CYP2B6 (unknown origin) assessed as spectral dissociation constant-2 | Homo sapiens | 5 | ALA5214950 | single protein format | Scientific Literature | |
5. | ALA5216989 | A | Drug metabolism assessed as CYP2B6 (unknown origin)-mediated d4-BuOH metabolite formation by measuring km | Homo sapiens | 2 | ALA5214950 | single protein format | Scientific Literature | |
6. | ALA5216993 | A | Drug metabolism assessed as CYP2B6 (unknown origin)-mediated d4-BuOH metabolite formation by measuring Kcat | Homo sapiens | 2 | ALA5214950 | single protein format | Scientific Literature | |
7. | ALA5216996 | A | Drug metabolism assessed as CYP2B6 (unknown origin)-mediated d4-BuOH metabolite formation by measuring intrinsic clearance | Homo sapiens | 2 | ALA5214950 | single protein format | Scientific Literature | |
8. | ALA5216998 | A | Inhibition of CYP2B6-mediated metabolism in human liver microsomes assessed as fold reduction in R,R-hydroxybupropion formation | Homo sapiens | 2 | ALA5214950 | microsome format | Scientific Literature | |
9. | ALA5217000 | A | Inhibition of CYP2B6-mediated metabolism in human hepatocytes assessed as reduction in R,R-hydroxybupropion formation | Homo sapiens | 2 | ALA5214950 | cell-based format | Scientific Literature | |
10. | ALA5217001 | A | Inhibition of CYP2B6-mediated metabolism in human hepatocytes assessed as reduction in erythro/threo-hydrobupropion formation | Homo sapiens | 2 | ALA5214950 | cell-based format | Scientific Literature |