# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5215668 | B | Inhibition of human recombinant integrin alphavbeta6 incubated for 1 hr by ELISA assay | Homo sapiens | 8 | ALA5214901 | protein complex format | Scientific Literature | |
2. | ALA5215669 | B | Inhibition of human recombinant integrin alphavbeta8 incubated for 1 hr by ELISA assay | Homo sapiens | 8 | ALA5214901 | assay format | Scientific Literature | |
3. | ALA5215670 | B | Inhibition of human recombinant integrin alphavbeta3 incubated for 1 hr by ELISA assay | Homo sapiens | 8 | ALA5214901 | protein complex format | Scientific Literature | |
4. | ALA5215671 | B | Inhibition of human recombinant integrin alpha5beta1 incubated for 1 hr by ELISA assay | Homo sapiens | 8 | ALA5214901 | protein complex format | Scientific Literature | |
5. | ALA5215672 | F | Antiviral activity against HSV-1 R8102 infected in HEK293T cells assessed as inhibition of viral replication using ONPG as substrate incubated for 1 hrs followed by viral infection measured after 90 mins by microplate reader analysis | Human alphaherpesvirus 1 | 2 | ALA5214901 | organism-based format | Scientific Literature | |
6. | ALA5215673 | F | Antiviral activity against HSV-1 R8102 infected in HEK293T cells assessed as inhibition of viral replication at 500 to 1000 uM using ONPG as substrate incubated for 1 hrs followed by viral infection measured after 90 mins by microplate reader analysis relative to control | Human alphaherpesvirus 1 | 1 | ALA5214901 | organism-based format | Scientific Literature | |
7. | ALA5215676 | F | Antiviral activity against HSV-1 K26GFP infected in J cells expressing nectin1 plus alphavbeta6/alphavbeta8 integrin at 700 uM incubated for 48 hrs followed by viral infection measured after 16 hrs by fluorescent microscopy | Human alphaherpesvirus 1 | 3 | ALA5214901 | organism-based format | Scientific Literature | |
8. | ALA5215677 | F | Antiviral activity against HSV-1 K26GFP infected in J cells expressing nectin1 plus alphavbeta6 integrin at 700 uM incubated for 48 hrs followed by viral infection measured after 16 hrs by fluorescent microscopy | Human alphaherpesvirus 1 | 3 | ALA5214901 | organism-based format | Scientific Literature | |
9. | ALA5215678 | F | Antiviral activity against HSV-1 K26GFP infected in J cells expressing nectin1 plus alphavbeta8 integrin at 700 uM incubated for 48 hrs followed by viral infection measured after 16 hrs by fluorescent microscopy | Human alphaherpesvirus 1 | 2 | ALA5214901 | organism-based format | Scientific Literature | |
10. | ALA5215679 | F | Antiviral activity against HSV-1 K26GFP infected in J cells expressing nectin1 plus alphavbeta6/alphavbeta8 integrin assessed as alphavbeta6/alphavbeta8 receptor internalization at 700 uM incubated for 1 hrs followed by viral infection by flow cytometry assay | Human alphaherpesvirus 1 | 2 | ALA5214901 | organism-based format | Scientific Literature | |
11. | ALA5215680 | B | Inhibition of HSV-1 soluble gH binding to alphavbeta6/alphavbeta8 integrin expressed in virus-infected J cells at 700 uM incubated for 1 hr by flow cytometry assay | Human alphaherpesvirus 1 | 2 | ALA5214901 | cell-based format | Scientific Literature | |
12. | ALA5215681 | B | Inhibition of HSV-1 soluble gB binding to alphavbeta6/alphavbeta8 integrin expressed in virus-infected J cells at 700 uM incubated for 1 hr by flow cytometry assay | Human alphaherpesvirus 1 | 2 | ALA5214901 | cell-based format | Scientific Literature |