# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5215278 | F | Antidiabetic activity in DIO mouse assessed as reduction in blood glucose at 300 nmol/kg, ip pretreated with compound and followed by glucose challenge and measured by oral glucose tolerance test | Mus musculus | 1 | ALA5214890 | organism-based format | Scientific Literature | |
2. | ALA5215282 | F | Antidiabetic activity in db/db mouse assessed as reduction in blood glucose at 300 nmol/kg, ip pretreated with compound and followed by glucose challenge and measured by oral glucose tolerance test | Mus musculus | 1 | ALA5214890 | organism-based format | Scientific Literature | |
3. | ALA5215285 | F | Antidiabetic activity in db/db mouse assessed as reduction in plasma insulin level at 300 nmol/kg, ip pretreated with compound and followed by glucose challenge and measured by oral glucose tolerance test | Mus musculus | 1 | ALA5214890 | organism-based format | Scientific Literature | |
4. | ALA5215292 | F | Antidiabetic activity in male DIO mouse assessed as reduction in acute food intake at 1000 nmol/kg, sc measured at 0 to 2 hrs post administration | Mus musculus | 1 | ALA5214890 | organism-based format | Scientific Literature | |
5. | ALA5215293 | F | Antidiabetic activity in male DIO mouse assessed as reduction in acute food intake at 1000 nmol/kg, sc measured at 2 to 24 hrs post administration | Mus musculus | 1 | ALA5214890 | organism-based format | Scientific Literature | |
6. | ALA5245916 | B | Agonist activity at mouse GCGR expressed in CHO cells assessed as increase in cAMP accumulation | Mus musculus | 11 | ALA5244248 | cell-based format | Scientific Literature | |
7. | ALA5245917 | B | Agonist activity at mouse GLP-1R expressed in CHO cells assessed as increase in cAMP accumulation | Mus musculus | 11 | ALA5244248 | cell-based format | Scientific Literature | |
8. | ALA5245918 | B | Agonist activity at mouse GCGR expressed in CHO cells assessed as increase in cAMP accumulation relative to glucagon | Mus musculus | 10 | ALA5244248 | cell-based format | Scientific Literature | |
9. | ALA5245919 | B | Agonist activity at mouse GLP-1R expressed in CHO cells assessed as increase in cAMP accumulation relative to GLP-1 | Mus musculus | 10 | ALA5244248 | cell-based format | Scientific Literature |