| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5218148 | B | Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assay | Homo sapiens | 45 | single protein format | Scientific Literature | ||
| 2. | ALA5218149 | B | Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assay | Homo sapiens | 45 | single protein format | Scientific Literature | ||
| 3. | ALA5218150 | B | Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assay | Homo sapiens | 29 | tissue-based format | Scientific Literature | ||
| 4. | ALA5218151 | P | Lipophilicity, logD of compound at pH 7.4 by Chromatography | 37 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA5218152 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 6. | ALA5218153 | A | Metabolism dependent inhibition of CYP3A4 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 7. | ALA5218154 | T | Inhibition of hERG | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 8. | ALA5218155 | A | Artificial membrane permeability of the compound | 33 | assay format | Scientific Literature | |||
| 9. | ALA5218157 | P | Solubility of the compound at pH 6.5 in fast state simulated intestinal fluid incubated for 16 hrs by HPLC analysis | 5 | small-molecule physicochemical format | Scientific Literature | |||
| 10. | ALA5218158 | A | Intrinsic clearance in rat hepatocytes after 60 mins by LC-MS/MS analysis | Rattus norvegicus | 9 | cell-based format | Scientific Literature | ||
| 11. | ALA5218159 | A | Intrinsic clearance in dog hepatocytes incubated upto 45 mins by LC-MS/MS analysis | Canis lupus familiaris | 8 | cell-based format | Scientific Literature | ||
| 12. | ALA5218160 | A | Intrinsic clearance in human hepatocytes measured after 120 mins by LC-MS/MS analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 13. | ALA5218172 | A | Clearance in Wistar Han rat blood at 3 mg/kg, po or 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA5218173 | A | Unbound clearance in Wistar Han rat blood at 3 mg/kg, po or 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA5218174 | A | Volume of distribution at steady state in Wistar Han rat at 3 mg/kg, po or 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA5218175 | A | Unbound volume of distribution at steady state in Wistar Han rat at 3 mg/kg, po or 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA5218176 | A | Half-life in Wistar Han rat at 3 mg/kg, po or 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA5218177 | A | Oral bioavailability in Wistar Han rat at 3 mg/kg measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA5218183 | A | Oral bioavailability in Beagle dog at 1.5 mg/kg measured upto 24 hrs by LC-MS/MS analysis | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA5218184 | A | Clearance in Beagle dog blood at 1.5 mg/kg, po or 0.5 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Canis lupus familiaris | 1 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!