| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5218133 | B | Binding affinity to PRMT5/MEP50 (unknown origin) assessed as inhibition constant by FITC- Competitive binding assay | Homo sapiens | 7 | protein complex format | Scientific Literature | ||
| 2. | ALA5218137 | B | Thermal stabilization of PRMT5/MEP50 (unknown origin) assessed as melting temperature by SYPRO Orange dye based thermal shift assay | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 3. | ALA5218139 | B | Inhibition of full length human ICLN/PRMT5 (unknown origin) protein-protein interaction by fluorescence polarization assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 4. | ALA5218141 | B | Inhibition of PRMT5/MEP50 in human Flp-In-T-REx-293 cells over-expressed with GFP-PRMT5 at 50 uM incubated for 2 hrs by immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5218142 | B | Inhibition of PRMT5/RioK1 protein-protein interaction in human Flp-In-T-REx-293 cells over-expressed with GFP-PRMT5 at 50 uM incubated for 2 hrs by immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5218143 | B | Inhibition of ICLN/PRMT5 protein-protein interaction in human Flp-In-T-REx-293 cells over-expressed with GFP-PRMT5 at 50 uM incubated for 2 hrs by immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5218144 | B | Inhibition of PRMT5/RioK1 protein-protein interaction in human Flp-In-T-REx-293 cells over-expressed with GFP-RioK1 at 50 uM incubated for 2 hrs by immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5218145 | B | Inhibition of ICLN/PRMT5 protein-protein interaction in human Flp-In-T-REx-293 cells over-expressed with GFP-pICln at 50 uM incubated for 2 hrs by immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5218146 | B | Inhibition of PRMT5/MEP50 (unknown origin) incubated for 1 to 2 hrs in presence of tracer 50 by competitive fluorescence polarization assay | Homo sapiens | 3 | protein complex format | Scientific Literature |
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