# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5217943 | B | Inhibition of human NNMT measured after 20 mins by luminescence based methyltransferase assay | Homo sapiens | 44 | single protein format | Scientific Literature | ||
2. | ALA5217944 | B | Inhibition of human NNMT in human K562 cells measured after 24 hrs by quantitative mass spectrometry | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
3. | ALA5217945 | A | Microsomal stability in human liver microsomes assessed as compound remaining after 60 mins by LC-MS/MS analysis | Homo sapiens | 7 | microsome format | Scientific Literature | ||
4. | ALA5217946 | A | Microsomal stability in mouse liver microsomes assessed as compound remaining after 60 mins by LC-MS/MS analysis | Mus musculus | 7 | microsome format | Scientific Literature | ||
5. | ALA5217947 | A | Half life in C57BL6/N mouse at 50 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 5 | organism-based format | Scientific Literature | ||
6. | ALA5217948 | A | Half life in C57BL6/N mouse at 10 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 5 | organism-based format | Scientific Literature | ||
7. | ALA5217949 | A | Tmax in C57BL6/N mouse at 50 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 6 | organism-based format | Scientific Literature | ||
8. | ALA5217950 | A | Cmax in C57BL6/N mouse at 50 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 6 | organism-based format | Scientific Literature | ||
9. | ALA5217951 | A | AUClast in C57BL6/N mouse at 50 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 6 | organism-based format | Scientific Literature | ||
10. | ALA5217952 | A | Clearance in C57BL6/N mouse at 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 6 | organism-based format | Scientific Literature | ||
11. | ALA5217953 | A | Oral bioavailability in C57BL6/N mouse at 50 mg/kg measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 6 | organism-based format | Scientific Literature |