# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5215721 | B | Inhibition of human IDO1 (12 to 403 aa) expressed in Escherichia coli Transetta (DE3) by nanodrop 2000c spectrophotometric analysis | Homo sapiens | 44 | ALA5214905 | assay format | Scientific Literature | |
2. | ALA5215722 | B | Inhibition of human TDO (19 to 388 aa) expressed in Escherichia coli Transetta (DE3) by nanodrop 2000c spectrophotometric analysis | Homo sapiens | 44 | ALA5214905 | assay format | Scientific Literature | |
3. | ALA5215723 | B | Inhibition of IDO1 in IFN-gamma induced overexpressing human HeLa cells | Homo sapiens | 3 | ALA5214905 | cell-based format | Scientific Literature | |
4. | ALA5215724 | B | Inhibition of TDO in overexpressing human SW48 cells | Homo sapiens | 3 | ALA5214905 | cell-based format | Scientific Literature | |
5. | ALA5215725 | B | Inhibition of TDO in overexpressing human A-172 cells | Homo sapiens | 3 | ALA5214905 | cell-based format | Scientific Literature | |
6. | ALA5215726 | A | Apparent permeability in MDCKII expressing MDR1 cells across apical to basolateral side | Canis lupus familiaris | 1 | ALA5214905 | cell-based format | Scientific Literature | |
7. | ALA5215727 | A | Apparent permeability in human Caco-2 expressing BCRP cells across apical to basolateral side | Homo sapiens | 1 | ALA5214905 | cell-based format | Scientific Literature | |
8. | ALA5215728 | A | Apparent permeability in human Caco-2 expressing BCRP cells across apical to basolateral side in presence of novobiocin | Homo sapiens | 1 | ALA5214905 | cell-based format | Scientific Literature | |
9. | ALA5215729 | A | Apparent permeability in MDCKII expressing MDR1 cells across basolateral to apical side | Canis lupus familiaris | 1 | ALA5214905 | cell-based format | Scientific Literature | |
10. | ALA5215730 | A | Apparent permeability in human Caco-2 expressing BCRP cells across basolateral to apical side | Homo sapiens | 1 | ALA5214905 | cell-based format | Scientific Literature | |
11. | ALA5215731 | A | Apparent permeability in human Caco-2 expressing BCRP cells across basolateral to apical side in presence of novobiocin | Homo sapiens | 1 | ALA5214905 | cell-based format | Scientific Literature | |
12. | ALA5215732 | A | Efflux ratio of apparent permeability across basolateral to apical side to apical to basolateral side in MDCKII expressing MDR1 cells | Canis lupus familiaris | 1 | ALA5214905 | cell-based format | Scientific Literature | |
13. | ALA5215733 | A | Efflux ratio of apparent permeability across basolateral to apical side to apical to basolateral side in human Caco-2 expressing BCRP cells | Homo sapiens | 1 | ALA5214905 | cell-based format | Scientific Literature | |
14. | ALA5215734 | A | Efflux ratio of apparent permeability across basolateral to apical side to apical to basolateral side in human Caco-2 expressing BCRP cells in presence of novobiocin | Homo sapiens | 1 | ALA5214905 | cell-based format | Scientific Literature | |
15. | ALA5215735 | A | Permeability in MDCKII expressing MDR1 cells across apical to basolateral side by measuring ratio of the final amount of the compound in donor and receiver chambers to the initial amount of the compound in the donor chamber relative to control | Canis lupus familiaris | 1 | ALA5214905 | cell-based format | Scientific Literature | |
16. | ALA5215736 | A | Permeability in human Caco-2 expressing BCRP cells across apical to basolateral side by measuring ratio of the final amount of the compound in donor and receiver chambers to the initial amount of the compound in the donor chamber relative to control | Homo sapiens | 1 | ALA5214905 | cell-based format | Scientific Literature | |
17. | ALA5215737 | A | Permeability in human Caco-2 expressing BCRP cells across apical to basolateral side by measuring ratio of the final amount of the compound in donor and receiver chambers to the initial amount of the compound in the donor chamber in presence of novobiocin relative to control | Homo sapiens | 1 | ALA5214905 | cell-based format | Scientific Literature | |
18. | ALA5215738 | A | Permeability in MDCKII expressing MDR1 cells across basolateral to apical side by measuring ratio of the final amount of the compound in donor and receiver chambers to the initial amount of the compound in the donor chamber relative to control | Canis lupus familiaris | 1 | ALA5214905 | cell-based format | Scientific Literature | |
19. | ALA5215739 | A | Permeability in human Caco-2 expressing BCRP cells across basolateral to apical side by measuring ratio of the final amount of the compound in donor and receiver chambers to the initial amount of the compound in the donor chamber relative to control | Homo sapiens | 1 | ALA5214905 | cell-based format | Scientific Literature | |
20. | ALA5215740 | A | Permeability in human Caco-2 expressing BCRP cells across basolateral to apical side by measuring ratio of the final amount of the compound in donor and receiver chambers to the initial amount of the compound in the donor chamber in presence of novobiocin relative to control | Homo sapiens | 1 | ALA5214905 | cell-based format | Scientific Literature |