| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5215844 | B | Inhibition of rat alpha3beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA5215845 | B | Inhibition of human alpha1beta1deltaepsilon nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA5215846 | B | Inhibition of human alpha2beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA5215847 | A | Stability in human serum assessed as compound remaining at 150 nM and incubated for 24 hrs by RP-HPLC method | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
| 5. | ALA5215848 | B | Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence of Ach stimulation by voltage-clamp based electrophysiological method | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA5215849 | B | Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 7. | ALA5215850 | B | Inhibition of rat alpha2beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5215851 | B | Inhibition of human alpha2beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5215852 | B | Inhibition of rat alpha2beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5215853 | B | Inhibition of human alpha3beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5215854 | B | Inhibition of human alpha3beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5215855 | B | Inhibition of rat alpha3beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5215856 | B | Inhibition of human alpha4beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5215857 | B | Inhibition of rat alpha4beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5215858 | B | Inhibition of human alpha4beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5215859 | B | Inhibition of rat alpha4beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA5215860 | B | Inhibition of human alpha6/alpha3beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5215861 | B | Inhibition of rat alpha6/alpha3beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5215862 | B | Inhibition of human alpha6/alpha3beta2beta3 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5215863 | B | Inhibition of rat alpha6/alpha3beta2beta3 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method | Rattus norvegicus | 1 | cell-based format | Scientific Literature |
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