# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5216796 | B | Agonist activity at FXR in HEK293T cells assessed as transcriptional activity by measuring fluorescence intensity by luciferase reporter assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
2. | ALA5216797 | F | Protection against Con-A induced autoimmune hepatitis mouse model assessed as reduction in AST level | Mus musculus | 5 | organism-based format | Scientific Literature | ||
3. | ALA5216798 | F | Protection against Con-A induced autoimmune hepatitis mouse model assessed as reduction in ALT level | Mus musculus | 5 | organism-based format | Scientific Literature | ||
4. | ALA5216799 | A | AUC (0 to t) in mouse at 5 mg/kg, iv | Mus musculus | 2 | organism-based format | Scientific Literature | ||
5. | ALA5216800 | A | AUCinfinity in mouse at 5 mg/kg, iv | Mus musculus | 2 | organism-based format | Scientific Literature | ||
6. | ALA5216802 | A | AUC (0 to t) in mouse at 100 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
7. | ALA5216804 | A | AUCinfinity in mouse at 100 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
8. | ALA5216806 | A | Clearance in mouse at 100 mg/kg, po or 5 mg/kg, iv | Mus musculus | 1 | organism-based format | Scientific Literature | ||
9. | ALA5216808 | A | Half life in mouse at 100 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
10. | ALA5216810 | A | Tmax in mouse at 100 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
11. | ALA5216812 | A | Cmax in mouse at 100 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
12. | ALA5216814 | A | Oral bioavailability in mouse at 100 mg/kg | Mus musculus | 1 | organism-based format | Scientific Literature |