# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5217314 | F | Antidepressant activity in ICR mouse assessed as reduction in immobility time at 0.6 mg/kg, po for 7 days by tail suspension test | Mus musculus | 1 | ALA5214965 | organism-based format | Scientific Literature | |
2. | ALA5217315 | F | Antidepressant activity in ICR mouse assessed as reduction in immobility time at 10 mg/kg, po for 7 days by tail suspension test | Mus musculus | 1 | ALA5214965 | organism-based format | Scientific Literature | |
3. | ALA5217316 | F | Antidepressant activity in ICR mouse assessed as reduction in immobility time at 0.6 mg/kg, po for 7 days by forced swimming test | Mus musculus | 1 | ALA5214965 | organism-based format | Scientific Literature | |
4. | ALA5217318 | B | Binding affinity to 5-HT6 receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 1 | ALA5214965 | assay format | Scientific Literature | |
5. | ALA5217319 | B | Inhibition of 5-HT1B receptor (unknown origin) | Homo sapiens | 1 | ALA5214965 | single protein format | Scientific Literature | |
6. | ALA5217320 | B | Inhibition of serotonin transporter in rat brain tissue assessed as inhibition of [3H]-5-hydroxytryptamine reuptake at 1 uM relative to control | Rattus norvegicus | 18 | ALA5214965 | tissue-based format | Scientific Literature | |
7. | ALA5217321 | B | Displacement of [3H]8-OH-DAPT from 5-HT1A receptor in human HEK293 cells at 1 uM measured after 60 mins by scintillation counting method relative to control | Homo sapiens | 18 | ALA5214965 | cell-based format | Scientific Literature | |
8. | ALA5217322 | A | Metabolic stability in human liver microsomes assessed as half life | Homo sapiens | 14 | ALA5214965 | microsome format | Scientific Literature | |
9. | ALA5217323 | A | Metabolic stability in human liver microsomes assessed as clearance | Homo sapiens | 14 | ALA5214965 | microsome format | Scientific Literature | |
10. | ALA5217324 | A | Metabolic stability in mouse liver microsomes assessed as half life | Mus musculus | 8 | ALA5214965 | microsome format | Scientific Literature | |
11. | ALA5217325 | A | Metabolic stability in mouse liver microsomes assessed as clearance | Mus musculus | 8 | ALA5214965 | microsome format | Scientific Literature | |
12. | ALA5217326 | B | Inhibition of serotonin transporter in rat brain tissue assessed as inhibition of [3H]-5-hydroxytryptamine reuptake | Rattus norvegicus | 5 | ALA5214965 | tissue-based format | Scientific Literature | |
13. | ALA5217327 | B | Displacement of [3H]8-OH-DAPT from 5-HT1A receptor in human HEK293 cells measured after 60 mins by scintillation counting method | Homo sapiens | 6 | ALA5214965 | cell-based format | Scientific Literature | |
14. | ALA5217328 | B | Inhibition of 5-HT1D receptor (unknown origin) | Homo sapiens | 1 | ALA5214965 | single protein format | Scientific Literature | |
15. | ALA5217329 | B | Inhibition of 5-HT2A receptor (unknown origin) | Homo sapiens | 1 | ALA5214965 | single protein format | Scientific Literature | |
16. | ALA5217330 | B | Inhibition of 5-HT2C receptor (unknown origin) | Homo sapiens | 1 | ALA5214965 | single protein format | Scientific Literature | |
17. | ALA5217331 | B | Inhibition of 5-HT3 receptor (unknown origin) | Homo sapiens | 1 | ALA5214965 | protein complex format | Scientific Literature | |
18. | ALA5217332 | B | Inhibition of 5-HT6 receptor (unknown origin) | Homo sapiens | 1 | ALA5214965 | assay format | Scientific Literature | |
19. | ALA5217333 | B | Inhibition of 5-HT7 receptor (unknown origin) | Homo sapiens | 1 | ALA5214965 | assay format | Scientific Literature | |
20. | ALA5217334 | B | Binding affinity to 5-HT7 receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 1 | ALA5214965 | assay format | Scientific Literature |