# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5217749 | B | Inhibition of N-terminal 6His-tagged FGFR4 (unknown origin) using Tyr04 peptide as substrate incubated for 1 hr in presence of ATP by FRET based Z'-LYTE assay | Homo sapiens | 32 | single protein format | Scientific Literature | ||
2. | ALA5217750 | B | Inhibition of FGFR1 (unknown origin) using Tyr04 peptide as substrate incubated for 1 hr in presence of ATP by FRET based Z'-LYTE assay | Homo sapiens | 32 | single protein format | Scientific Literature | ||
3. | ALA5217751 | B | Inhibition of FGFR2 (unknown origin) using Tyr04 peptide as substrate incubated for 1 hr in presence of ATP by FRET based Z'-LYTE assay | Homo sapiens | 32 | single protein format | Scientific Literature | ||
4. | ALA5217752 | B | Inhibition of FGFR3 (unknown origin) using Tyr04 peptide as substrate incubated for 1 hr in presence of ATP by FRET based Z'-LYTE assay | Homo sapiens | 32 | single protein format | Scientific Literature | ||
5. | ALA5217753 | F | Antiproliferative activity against mouse BaF3 cells transfected with human FGFR4 assessed as reduction in cell viability measured after 72 hrs by CCK-8 method | Mus musculus | 32 | cell-based format | Scientific Literature | ||
6. | ALA5217754 | F | Antiproliferative activity against human Hep3B cells assessed as inhibition of cell growth measured after 5 days by SRB analysis | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
7. | ALA5217755 | F | Antiproliferative activity against human NCI-H1299 cells assessed as inhibition of cell growth measured after 5 days by SRB analysis | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
8. | ALA5217756 | F | Antiproliferative activity against human JHH7 cells assessed as inhibition of cell growth measured after 5 days by SRB analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
9. | ALA5217757 | F | Antiproliferative activity against human Huh-7 cells assessed as inhibition of cell growth measured after 5 days by SRB analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
10. | ALA5217758 | B | Inhibition of FGFR4 V550L mutant (unknown origin) expressed in Escherichia coli Rosetta2 (DE3) (NEB) cells in presence of ATP | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
11. | ALA5217759 | B | Inhibition of FGFR4 V550M mutant (unknown origin) expressed in Escherichia coli Rosetta2 (DE3) (NEB) cells in presence of ATP | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
12. | ALA5217760 | F | Antiproliferative activity against mouse BaF3 cells transfected with FGFR4 V550L mutant assessed as reduction in cell viability measured after 72 hrs by CCK-8 method | Mus musculus | 9 | cell-based format | Scientific Literature | ||
13. | ALA5217761 | F | Antiproliferative activity against mouse BaF3 cells transfected with FGFR4 V550M mutant assessed as reduction in cell viability measured after 72 hrs by CCK-8 method | Mus musculus | 9 | cell-based format | Scientific Literature | ||
14. | ALA5217762 | A | Half life in ICR mouse at 2 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
15. | ALA5217763 | A | Half life in ICR mouse at 10 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
16. | ALA5217764 | A | Tmax in ICR mouse at 2 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
17. | ALA5217765 | A | Tmax in ICR mouse at 10 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
18. | ALA5217766 | A | Cmax in ICR mouse at 2 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
19. | ALA5217767 | A | Cmax in ICR mouse at 10 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
20. | ALA5217768 | A | AUC (0 to t) in ICR mouse at 2 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature |