# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5216894 | A | Permeability of compound by PAMPA-BBB assay | 9 | assay format | Scientific Literature | |||
2. | ALA5216898 | F | Reversible inhibition of MAO-B in mouse brain assessed as MAO-B activity recovered at 24 hrs at 10 mg/kg when administered as single dose | Mus musculus | 2 | organism-based format | Scientific Literature | ||
3. | ALA5216899 | F | Reversible inhibition of MAO-B in mouse brain assessed as MAO-B activity recovered within 5 hrs at 10 mg/kg when administered as single dose | Mus musculus | 2 | organism-based format | Scientific Literature | ||
4. | ALA5216900 | B | Specificity index, ratio of IC50 for inhibition of human MAO-A to IC50 for inhibition of MAO-B | Homo sapiens | 19 | assay format | Scientific Literature | ||
5. | ALA5216901 | F | In vivo inhibition of MAO-B in resperine-induced mouse assessed as decrease in MAO-B activity in brain at 10 mg/kg | Mus musculus | 4 | organism-based format | Scientific Literature | ||
6. | ALA5216902 | B | Inhibition of recombinant human MAO-B | Homo sapiens | 25 | single protein format | Scientific Literature | ||
7. | ALA5216903 | B | Inhibition of human MAO-A | Homo sapiens | 19 | single protein format | Scientific Literature | ||
8. | ALA5216904 | T | Cytotoxicity against human SH-SY5Y cells at 1 to 80 uM by MTT assay | Homo sapiens | 6 | cell-based format | Scientific Literature |