# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5216850 | B | Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric method | Mycobacterium tuberculosis | 28 | ALA5214942 | single protein format | Scientific Literature | |
2. | ALA5216851 | B | Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins at 50 uM and measured by spectrophotometric method relative to control | Mycobacterium tuberculosis | 23 | ALA5214942 | single protein format | Scientific Literature | |
3. | ALA5216852 | F | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv measured by microplate alamar blue assay | Mycobacterium tuberculosis | 9 | ALA5214942 | organism-based format | Scientific Literature | |
4. | ALA5216853 | T | Cytotoxicity against African green monkey Vero cells after 48 hrs by MTT assay | Chlorocebus sabaeus | 9 | ALA5214942 | cell-based format | Scientific Literature | |
5. | ALA5216854 | T | Cytotoxicity against mouse J774.A1 cells after 48 hrs by MTT assay | Mus musculus | 9 | ALA5214942 | cell-based format | Scientific Literature | |
6. | ALA5216855 | B | Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpA using pNPP as substrate at 50 uM incubated for 10 mins and measured by spectrophotometric method relative to control | Mycobacterium tuberculosis | 7 | ALA5214942 | single protein format | Scientific Literature | |
7. | ALA5216856 | B | Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpA using pNPP as substrate incubated for 10 mins and measured by spectrophotometric method | Mycobacterium tuberculosis | 7 | ALA5214942 | single protein format | Scientific Literature | |
8. | ALA5216857 | B | Inhibition of recombinant human PTP1B using pNPP as substrate preincubated for 5 mins followed by substrate addition assessed as reduction in p-nitrophenol release at 50 uM relative to control | Homo sapiens | 7 | ALA5214942 | single protein format | Scientific Literature | |
9. | ALA5216858 | B | Inhibition of recombinant human PTP1B using pNPP as substrate preincubated for 5 mins followed by substrate addition assessed as reduction in p-nitrophenol release | Homo sapiens | 7 | ALA5214942 | single protein format | Scientific Literature | |
10. | ALA5216859 | B | Non-competitive inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate | Mycobacterium tuberculosis | 1 | ALA5214942 | single protein format | Scientific Literature | |
11. | ALA5216860 | F | Antimycobacterial activity against Mycobacterium tuberculosis infected in mouse J774.A1 cells assessed as reduction in intracellular bacterial burden at 5 ug/ml measured by colony counting method | Mycobacterium tuberculosis | 1 | ALA5214942 | organism-based format | Scientific Literature | |
12. | ALA5216861 | F | Antimycobacterial activity against Mycobacterium tuberculosis infected in mouse J774.A1 cells assessed as reduction in intracellular bacterial burden at 1 to 10 ug/ml measured by colony counting method | Mycobacterium tuberculosis | 1 | ALA5214942 | organism-based format | Scientific Literature |