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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5217493 F Antiviral activity against Enterovirus D68 infected in human RD cells assessed as inhibition of viral replication at 2 uM pretreated with virus for 1 hr followed by compound addition for 1 hr by qRT-PCR analysis enterovirus D68 1 ALA5214977 organism-based format Scientific Literature 2. ALA5217494 F Antiviral activity against Enterovirus-D68 STL-2014-12 infected in human RD cells assessed as reduction in virus induced cytopathic effect by measuring ATP level incubated for 72 hrs by cell titer-glo luminescent cell viability assay enterovirus D68 54 ALA5214977 organism-based format Scientific Literature 3. ALA5217495 F Cytotoxicity against human RD cells assessed as inhibition of cell viability by measuring ATP level incubated for 72 hrs by cell titer-glo luminescent cell viability assay Homo sapiens 47 ALA5214977 cell-based format Scientific Literature 4. ALA5217496 T Selectivity index, ratio of CC50 for human RD cells to EC50 for Enterovirus-D68 STL-2014-12 infected in human RD cells to 49 ALA5214977 cell-based format Scientific Literature 5. ALA5217503 A C0 in Sprague-Dawley rat at 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 ALA5214977 organism-based format Scientific Literature 6. ALA5217504 A Half life in Sprague-Dawley rat at 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 ALA5214977 organism-based format Scientific Literature 7. ALA5217505 A Clearance in Sprague-Dawley rat at 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 ALA5214977 organism-based format Scientific Literature 8. ALA5217506 A AUC(0 to t) in Sprague-Dawley rat at 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 ALA5214977 organism-based format Scientific Literature 9. ALA5217507 A AUC (0 to infinity) in Sprague-Dawley rat at 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 ALA5214977 organism-based format Scientific Literature 10. ALA5217508 A Half life in Sprague-Dawley rat at 5 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 ALA5214977 organism-based format Scientific Literature 11. ALA5217509 A Cmax in Sprague-Dawley rat at 5 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 ALA5214977 organism-based format Scientific Literature 12. ALA5217510 A Tmax in Sprague-Dawley rat at 5 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 ALA5214977 organism-based format Scientific Literature 13. ALA5217511 A AUC (0 to t) in Sprague-Dawley rat at 5 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 ALA5214977 organism-based format Scientific Literature 14. ALA5217512 A AUC (0 to infinity) in Sprague-Dawley rat at 5 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 ALA5214977 organism-based format Scientific Literature 15. ALA5217513 A Oral bioavailability in Sprague-Dawley rat at 5 mg/kg measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 ALA5214977 organism-based format Scientific Literature 16. ALA5217517 A Metabolic stability in rat liver microsomes assessed as intrinsic clearance at 1 uM incubated upto 60 mins in presence of NADPH by LC-MS/MS analysis Rattus norvegicus 1 ALA5214977 microsome format Scientific Literature 17. ALA5217518 A Metabolic stability in Beagle dog liver microsomes assessed as intrinsic clearance at 1 uM incubated upto 60 mins in presence of NADPH by LC-MS/MS analysis Canis lupus familiaris 1 ALA5214977 microsome format Scientific Literature 18. ALA5217519 A Metabolic stability in human liver microsomes assessed as intrinsic clearance at 1 uM incubated upto 60 mins in presence of NADPH by LC-MS/MS analysis Homo sapiens 1 ALA5214977 microsome format Scientific Literature 19. ALA5217520 A Metabolic stability in rat liver microsomes assessed as half life at 1 uM incubated upto 60 mins in presence of NADPH by LC-MS/MS analysis Rattus norvegicus 1 ALA5214977 microsome format Scientific Literature 20. ALA5217521 A Metabolic stability in Beagle dog liver microsomes assessed as half life at 1 uM incubated upto 60 mins in presence of NADPH by LC-MS/MS analysis Canis lupus familiaris 1 ALA5214977 microsome format Scientific Literature