# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5217244 | B | Inhibition of AKT1 (unknown origin) preincubated for 20 mins followed by [33P]-ATP addition measured after 120 mins by hotspot kinase assay | Homo sapiens | 4 | ALA5214961 | single protein format | Scientific Literature | |
2. | ALA5217245 | B | Inhibition of AKT2 (unknown origin) preincubated for 20 mins followed by [33P]-ATP addition measured after 120 mins by hotspot kinase assay | Homo sapiens | 4 | ALA5214961 | single protein format | Scientific Literature | |
3. | ALA5217246 | B | Inhibition of AKT3 (unknown origin) preincubated for 20 mins followed by [33P]-ATP addition measured after 120 mins by hotspot kinase assay | Homo sapiens | 4 | ALA5214961 | single protein format | Scientific Literature | |
4. | ALA5217250 | B | Induction of AKT degradation in MS21-resistant human SW620 cells harboring KRAS/BRAF mutant assessed as reduction in total AKT level at upto 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 3 | ALA5214961 | cell-based format | Scientific Literature | |
5. | ALA5217268 | B | Induction of AKT degradation in human SW620 cells assessed as reduction in total AKT level at 1 uM measured after 18 hrs by TMT-MS analysis | Homo sapiens | 2 | ALA5214961 | cell-based format | Scientific Literature | |
6. | ALA5217269 | B | Inhibition of PRAS40 phosphorylation in human SW620 cells at 1 uM measured after 18 hrs by TMT-MS analysis | Homo sapiens | 2 | ALA5214961 | cell-based format | Scientific Literature |