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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5218029 B Inhibition of 15-PGDH (unknown origin) using NAD as substrate measured for 3.5 mins Homo sapiens 55 ALA5214995 single protein format Scientific Literature 2. ALA5218030 P Aqueous solubility of the compound under shaking condition by LC-MS/MS analysis 5 ALA5214995 small-molecule physicochemical format Scientific Literature 3. ALA5218031 A Metabolic stability in ICR/CD-1 mouse liver S9 fraction assessed as half life at 2 uM preincubated for 5 mins followed by NADPH regenerating system addition by LC-MS/MS analysis Mus musculus 5 ALA5214995 subcellular format Scientific Literature 4. ALA5218032 A Cmax in CD-1 mouse at 10 mg/kg,ip measured upto 1440 mins by LC-MS/MS analysis Mus musculus 3 ALA5214995 organism-based format Scientific Literature 5. ALA5218033 A AUC in CD-1 mouse at 10 mg/kg,ip measured upto 1440 mins by LC-MS/MS analysis Mus musculus 3 ALA5214995 organism-based format Scientific Literature 6. ALA5218034 A Cmax in CD-1 mouse at 10 mg/kg,po measured upto 1440 mins by LC-MS/MS analysis Mus musculus 1 ALA5214995 organism-based format Scientific Literature 7. ALA5218035 A AUC in CD-1 mouse at 10 mg/kg,po measured upto 1440 mins by LC-MS/MS analysis Mus musculus 1 ALA5214995 organism-based format Scientific Literature 8. ALA5218036 A Oral bioavailability in CD-1 mouse at 10 mg/kg measured upto 1440 mins by LC-MS/MS analysis Mus musculus 1 ALA5214995 organism-based format Scientific Literature 9. ALA5218037 A Cmax in CD-1 mouse at 5 mg/kg,iv measured upto 1440 mins by LC-MS/MS analysis Mus musculus 1 ALA5214995 organism-based format Scientific Literature 10. ALA5218038 A AUC in CD-1 mouse at 5 mg/kg,iv measured upto 1440 mins by LC-MS/MS analysis Mus musculus 1 ALA5214995 organism-based format Scientific Literature 11. ALA5218039 A Clearance in CD-1 mouse at 5 mg/kg,iv measured upto 1440 mins by LC-MS/MS analysis Mus musculus 1 ALA5214995 organism-based format Scientific Literature 12. ALA5218041 B Induction of PGE2 in IL-1beta stimulated human A549 cells at 20 nM incubated for 24 hrs by ELISA assay Homo sapiens 2 ALA5214995 cell-based format Scientific Literature 13. ALA5218043 F Invivo activation of PGE2 in C57BL/6J mouse colon tissue assessed as increase in PGE2 level at 5 mg/kg,ip measured after 3 hrs by ELISA Mus musculus 2 ALA5214995 organism-based format Scientific Literature 14. ALA5218044 F Invivo activation of PGE2 in C57BL/6J mouse lung tissue assessed as increase in PGE2 level at 5 mg/kg,ip measured after 3 hrs by ELISA Mus musculus 2 ALA5214995 organism-based format Scientific Literature 15. ALA5218045 F Invivo activation of PGE2 in C57BL/6J mouse colon tissue assessed as increase in PGE2 level at 2.5 mg/kg,ip measured after 3 hrs by ELISA Mus musculus 1 ALA5214995 organism-based format Scientific Literature 16. ALA5218046 F Invivo activation of PGE2 in C57BL/6J mouse lung tissue assessed as increase in PGE2 level at 2.5 mg/kg,ip measured after 3 hrs by ELISA Mus musculus 1 ALA5214995 organism-based format Scientific Literature 17. ALA5218047 F Invivo inhibition of 15-PGDH in C57BL/6J mouse colon tissue at 20 mg/kg,po measured after 30 mins by tritium-release assay Mus musculus 1 ALA5214995 organism-based format Scientific Literature 18. ALA5218048 F Invivo inhibition of 15-PGDH in C57BL/6J mouse colon tissue at 20 mg/kg,po measured after 90 mins by tritium-release assay Mus musculus 1 ALA5214995 organism-based format Scientific Literature 19. ALA5218049 F Invivo inhibition of 15-PGDH in C57BL/6J mouse colon tissue at 40 mg/kg,po measured after 30 mins by tritium-release assay Mus musculus 1 ALA5214995 organism-based format Scientific Literature 20. ALA5218050 F Invivo inhibition of 15-PGDH in C57BL/6J mouse colon tissue at 40 mg/kg,po measured after 90 mins by tritium-release assay Mus musculus 1 ALA5214995 organism-based format Scientific Literature