# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5217227 | Functional | Antiproliferative activity against human SW620 cells harboring KRAS mutant assessed as inhibition of cell growth incubated for 5 days by IncuCyte live-cell imaging analysis | Homo sapiens | 3 | ALA5214961 | cell-based format | Scientific Literature | |
2. | ALA5217228 | Functional | Inhibition of colony formation in human SW620 cells harboring KRAS mutant at 0.03 to 10 uM incubated for 14 days with media replacement for every 2 days by crystal violet staining based analysis | Homo sapiens | 4 | ALA5214961 | cell-based format | Scientific Literature | |
3. | ALA5217244 | Binding | Inhibition of AKT1 (unknown origin) preincubated for 20 mins followed by [33P]-ATP addition measured after 120 mins by hotspot kinase assay | Homo sapiens | 4 | ALA5214961 | single protein format | Scientific Literature | |
4. | ALA5217245 | Binding | Inhibition of AKT2 (unknown origin) preincubated for 20 mins followed by [33P]-ATP addition measured after 120 mins by hotspot kinase assay | Homo sapiens | 4 | ALA5214961 | single protein format | Scientific Literature | |
5. | ALA5217246 | Binding | Inhibition of AKT3 (unknown origin) preincubated for 20 mins followed by [33P]-ATP addition measured after 120 mins by hotspot kinase assay | Homo sapiens | 4 | ALA5214961 | single protein format | Scientific Literature | |
6. | ALA5217250 | Binding | Induction of AKT degradation in MS21-resistant human SW620 cells harboring KRAS/BRAF mutant assessed as reduction in total AKT level at upto 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 3 | ALA5214961 | cell-based format | Scientific Literature |