# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5217994 | B | Inhibition of full-length P300 (unknown origin) using ARTKQTARKSTGGKAPRKQLAGG-K(Biotin)-amide as substrate preincubated for 60 mins followed by substrate addition and measured by RapdiFire-MS/MS analysis | Homo sapiens | 28 | ALA5214994 | single protein format | Scientific Literature | |
2. | ALA5217995 | B | Inhibition of full-length P300 (1 to 2414 residues) (unknown origin) using ARTKQTARKSTGGKAPRKQLAGG-K(Biotin)-amide as substrate preincubated for 60 mins followed by substrate addition and measured by scintillation proximity assay | Homo sapiens | 2 | ALA5214994 | single protein format | Scientific Literature | |
3. | ALA5217996 | B | Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assay | Homo sapiens | 27 | ALA5214994 | cell-based format | Scientific Literature | |
4. | ALA5217997 | P | Lipophilicity, log D of the compound at pH 7.4 by chromatographic method | 18 | ALA5214994 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA5218005 | A | Cmax in male Wistar Han rat at 0.6 mg/kg, iv measured after 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA5214994 | organism-based format | Scientific Literature | |
6. | ALA5218006 | A | AUC (0 to infinity) in male Wistar Han rat at 0.6 mg/kg, iv measured after 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA5214994 | organism-based format | Scientific Literature | |
7. | ALA5218007 | A | Clearance in male Wistar Han rat at 0.6 mg/kg, iv measured after 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA5214994 | organism-based format | Scientific Literature | |
8. | ALA5218008 | A | Volume of distribution at steady state in male Wistar Han rat at 0.6 mg/kg, iv measured after 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA5214994 | organism-based format | Scientific Literature | |
9. | ALA5218009 | A | Half-life in male Wistar Han rat at 0.6 mg/kg, iv measured after 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA5214994 | organism-based format | Scientific Literature | |
10. | ALA5218010 | A | Mean residence time in male Wistar Han rat at 0.6 mg/kg, iv measured after 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA5214994 | organism-based format | Scientific Literature |