# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5217723 | B | Inhibition of Cathepsin K (unknown origin) assessed as inhibition of AFC release using sequence LR labelled with AFC as substrate by fluorescence based analysis | Homo sapiens | 5 | ALA5214986 | single protein format | Scientific Literature | |
2. | ALA5217724 | B | Inhibition of Cathepsin K (unknown origin) assessed as inhibition of AFC release at 1 uM using sequence LR labelled with AFC as substrate by fluorescence based analysis | Homo sapiens | 16 | ALA5214986 | single protein format | Scientific Literature | |
3. | ALA5217725 | B | Inhibition of Cathepsin K (unknown origin) assessed as inhibition of AFC release at 10 uM using sequence LR labelled with AFC as substrate by fluorescence based analysis | Homo sapiens | 16 | ALA5214986 | single protein format | Scientific Literature | |
4. | ALA5217726 | B | Inhibition of Cathepsin S (unknown origin) assessed as inhibition of AFC release using sequence VVR labelled with AFC as substrate by fluorescence based analysis | Homo sapiens | 5 | ALA5214986 | single protein format | Scientific Literature | |
5. | ALA5217727 | B | Inhibition of Cathepsin B (unknown origin) assessed as inhibition of AFC release using sequence RR labelled with AFC as substrate by fluorescence based analysis | Homo sapiens | 5 | ALA5214986 | single protein format | Scientific Literature | |
6. | ALA5217728 | B | Selectivity index, ratio of IC50 for Cathepsin S (unknown origin) to IC50 for Cathepsin K (unknown origin) by fluorescence based analysis | Homo sapiens | 2 | ALA5214986 | protein format | Scientific Literature | |
7. | ALA5217729 | B | Selectivity index, ratio of IC50 for Cathepsin B (unknown origin) to IC50 for Cathepsin K (unknown origin) by fluorescence based analysis | Homo sapiens | 2 | ALA5214986 | protein format | Scientific Literature | |
8. | ALA5217730 | B | Reversible inhibition of Cathepsin K (unknown origin) assessed as inhibition of AFC release using sequence LR labelled with AFC as substrate preincubated with enzyme for 10 to 60 mins followed by substrate addition by fluorescence based analysis | Homo sapiens | 1 | ALA5214986 | single protein format | Scientific Literature |