# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5217581 | Binding | Inhibition of N-terminal his-tagged human recombinant BCAT1 expressed in Escherichia coli BL21(DE3) cells using leucine and alpha-KG as substrate in presence of NADH by fluorescence assay | Homo sapiens | 39 | ALA5214979 | cell-based format | Scientific Literature | |
2. | ALA5217583 | ADME | Apparent permeability of the compound from apical to basolateral side in human Caco-2 cells incubated for 2 hrs by LC-MS/MS analysis | Homo sapiens | 15 | ALA5214979 | cell-based format | Scientific Literature | |
3. | ALA5217584 | ADME | Efflux ratio of apparent permeability in human Caco-2 cells incubated for 2 hrs by LC-MS/MS analysis | Homo sapiens | 16 | ALA5214979 | cell-based format | Scientific Literature | |
4. | ALA5217585 | Physicochemical | Dissociation constant, pKa of the compound | 16 | ALA5214979 | small-molecule physicochemical format | Scientific Literature |