| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5216674 | B | Agonist activity at STING in human THP-1 cells harboring IRF-inducible luciferase reporter construct assessed as fold change in ISG signalling at 20 uM incubated for 12 hrs by Quanti-luc reagent based assay relative to control | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 2. | ALA5216676 | B | Binding affinity to recombinant human STING H232 variant expressed in Escherichia coli BL21 (DE3) assessed as thermal stabilization by measuring change in melting temperature at 2 mM incubated for 30 mins by SYPRO orange dye based differential scanning fluorimetry assay | Homo sapiens | 18 | assay format | Scientific Literature |
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