#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3579956	Binding	Inhibition of human placental HexA using pNPGlcNAc substrate	Homo sapiens	17	ALA3576868	assay format	Scientific Literature
2.	ALA3579957	Binding	Chaperoning efficacy at HexA alpha G269S mutant in ATSD patient fibroblasts assessed as maximum increase in enzyme activity using MUGS substrate incubated for 1 to 2 hrs by spectrofluorometry relative to control	Homo sapiens	9	ALA3576868	single protein format	Scientific Literature
3.	ALA3579962	Binding	Chaperoning efficacy at HexA alpha G269S mutant in ATSD patient fibroblasts assessed as drug level causing maximum increase in enzyme activity using MUGS substrate incubated for 1 to 2 hrs by spectrofluorometry relative to control	Homo sapiens	7	ALA3576868	single protein format	Scientific Literature
4.	ALA3579963	Toxicity	Toxicity against ATSD patient fibroblasts assessed as reduction in beta-galactosidase activity at >400 uM	Homo sapiens	8	ALA3576868	cell-based format	Scientific Literature
5.	ALA3579964	Toxicity	Toxicity against ATSD patient fibroblasts assessed as reduction in beta-galactosidase activity at	Homo sapiens	4	ALA3576868	cell-based format	Scientific Literature
6.	ALA668409	Binding	Inhibition of the C59R+S108N mutant of dihydrofolate reductase (DHFR)	Plasmodium falciparum	43	ALA1135602	single protein format	Scientific Literature
7.	ALA668410	Binding	Inhibition of the S108N mutant of dihydrofolate reductase (DHFR)	Plasmodium falciparum	43	ALA1135602	single protein format	Scientific Literature
8.	ALA668411	Binding	Inhibition of the wild-type dihydrofolate reductase (DHFR)	Plasmodium falciparum	43	ALA1135602	single protein format	Scientific Literature
9.	ALA668418	Binding	Inhibition of the C59R+S108N mutant of dihydrofolate reductase (DHFR) relative to Pyr.	Plasmodium falciparum	6	ALA1135602	single protein format	Scientific Literature
10.	ALA668423	Binding	Inhibition of the S108N mutant of dihydrofolate reductase (DHFR) relative to Pyr.	Plasmodium falciparum	6	ALA1135602	single protein format	Scientific Literature
11.	ALA667612	Binding	Inhibition of the wild-type dihydrofolate reductase (DHFR) relative to Pyr.	Plasmodium falciparum	6	ALA1135602	single protein format	Scientific Literature
12.	ALA849932	Binding	Ratio of Inhibition of the C59R+S108N mutant of dihydrofolate reductase (DHFR) to inhibition of wild type dihydrofolate reductase.	Plasmodium falciparum	40	ALA1135602	single protein format	Scientific Literature
13.	ALA848232	Binding	Ratio of Inhibition of the S108N mutant of dihydrofolate reductase (DHFR) to inhibition of wild type dihydrofolate reductase.	Plasmodium falciparum	40	ALA1135602	single protein format	Scientific Literature
14.	ALA849104	Functional	IC50 ratio against Plasmodium falciparum K1CB1/TM4	Plasmodium falciparum	43	ALA1135602	organism-based format	Scientific Literature
15.	ALA828776	Binding	Inhibition constant against Plasmodium falciparum dihydrofolate reductase	Plasmodium falciparum	52	ALA1138679	single protein format	Scientific Literature
16.	ALA767132	Functional	In vitro antiplasmodial activity (IC50) against Plasmodium falciparum wtTM4/8.2	Plasmodium falciparum	43	ALA1135602	organism-based format	Scientific Literature
17.	ALA766285	Functional	Relative antiplasmodial activity (IC50) compared to Pyr against Plasmodium falciparum K1CB1 DHFR double-mutant (C59R/S108N)	Plasmodium falciparum	6	ALA1135602	organism-based format	Scientific Literature
18.	ALA766289	Functional	In vitro relative antiplasmodial activity (IC50) compared to Pyr against Plasmodium falciparum TM4/8.2 wild-type	Plasmodium falciparum	6	ALA1135602	organism-based format	Scientific Literature
19.	ALA762995	Functional	Antiplasmodial activity IC50 against Plasmodium falciparum K1CB1 DHFR double-mutant (C59R/S10)	Plasmodium falciparum	43	ALA1135602	assay format	Scientific Literature