| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5249090 | F | Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 28 | ALA5247592 | cell-based format | Scientific Literature | |
| 2. | ALA5249091 | T | Cytotoxicity against HEK293T cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 28 | ALA5247592 | cell-based format | Scientific Literature | |
| 3. | ALA5249092 | T | Cytotoxicity against HUVEC cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 28 | ALA5247592 | cell-based format | Scientific Literature | |
| 4. | ALA5249093 | T | Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 28 | ALA5247592 | cell-based format | Scientific Literature | |
| 5. | ALA5249094 | B | PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as reduction in VEGFR2 protein level by measuring maximal efficacy at 0.15 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5247592 | cell-based format | Scientific Literature | |
| 6. | ALA5249095 | B | Inhibition of VEGFR2 (unknown origin) at 1 uM by caliper mobility shift assay relative to control | Homo sapiens | 3 | ALA5247592 | single protein format | Scientific Literature | |
| 7. | ALA5249096 | B | PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as reduction in VEGFR2 protein level incubated for 24 hrs by Western blot analysis | Homo sapiens | 15 | ALA5247592 | cell-based format | Scientific Literature | |
| 8. | ALA5249099 | B | PROTAC activity at VHL/VEGFR2 in HUVEC cells assessed as reduction in VEGFR2 protein level incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5247592 | cell-based format | Scientific Literature | |
| 9. | ALA5249100 | B | PROTAC activity at VHL/VEGFR2 in HUVEC cells assessed as reduction in VEGFR2 protein level by measuring maximal efficacy at 0.007 to 10 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5247592 | cell-based format | Scientific Literature | |
| 10. | ALA5249101 | B | PROTAC activity at VHL/VEGFR2 in HUVEC cells assessed as reduction in VEGFR2 protein level at 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5247592 | cell-based format | Scientific Literature | |
| 11. | ALA5249102 | B | PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as reduction in VEGFR2 protein level at 1 uM by Western blot analysis | Homo sapiens | 1 | ALA5247592 | cell-based format | Scientific Literature | |
| 12. | ALA5249103 | B | PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as induction of VEGFR2 degradation at 1 uM measured after 4 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5247592 | cell-based format | Scientific Literature | |
| 13. | ALA5249104 | B | PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as induction of VEGFR2 degradation at 1 uM measured after 8 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5247592 | cell-based format | Scientific Literature | |
| 14. | ALA5249105 | B | PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as induction of VEGFR2 degradation at 1 uM measured after 12 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5247592 | cell-based format | Scientific Literature | |
| 15. | ALA5249106 | B | PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as induction of VEGFR2 degradation at 1 uM measured after 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5247592 | cell-based format | Scientific Literature | |
| 16. | ALA5249107 | B | PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as induction of VEGFR2 degradation at 1 uM measured after 36 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5247592 | cell-based format | Scientific Literature | |
| 17. | ALA5249108 | B | PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as residual activity by measuring VEGFR2 expression level at 1 uM incubated for 24 hrs followed by compound washout and measured after 8 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5247592 | cell-based format | Scientific Literature | |
| 18. | ALA5249109 | B | PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as residual activity by measuring VEGFR2 expression level at 1 uM incubated for 24 hrs followed by compound washout and measured after 36 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5247592 | cell-based format | Scientific Literature | |
| 19. | ALA5249110 | B | PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as residual activity by measuring VEGFR2 expression level at 1 uM incubated for 24 hrs followed by compound washout and measured after 4 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5247592 | cell-based format | Scientific Literature | |
| 20. | ALA5249111 | B | PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as residual activity by measuring VEGFR2 expression level at 1 uM incubated for 24 hrs followed by compound washout and measured after 12 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5247592 | cell-based format | Scientific Literature |
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