# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5249257 | F | Cytotoxicity against human MOLM-13 cells assessed as reduction of cell viability incubated for 3 days by CellTiter-Glo assay | Homo sapiens | 65 | ALA5247596 | cell-based format | Scientific Literature | |
2. | ALA5249258 | A | Metabolic stability in mouse liver microsomes assessed as intrinsic clearance at 1 uM incubated upto 60 mins in presence of NADP by LC-MS analysis | Mus musculus | 11 | ALA5247596 | microsome format | Scientific Literature | |
3. | ALA5249259 | A | AUC(0 to 6 hrs) in mouse at 10 mg/kg, po administered via gavage measured upto 24 hrs by LC/MS-MS analysis | Mus musculus | 5 | ALA5247596 | organism-based format | Scientific Literature | |
4. | ALA5249260 | F | Antitumor activity against human HT-1080 cells xenografted in mouse assessed as tumor growth inhibition at 50 mg/kg, po bid measured for 14 days relative to control | Homo sapiens | 1 | ALA5247596 | organism-based format | Scientific Literature | |
5. | ALA5249261 | F | Antitumor activity against human HT-1080 cells xenografted in mouse assessed as tumor growth inhibition at 10 mg/kg, po bid measured for 14 days relative to control | Homo sapiens | 1 | ALA5247596 | organism-based format | Scientific Literature |