The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
The page will load shortly, Thanks for your patience!
# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5250064 Binding Inhibition of human NOX4 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based microplate reader analysis Homo sapiens 24 ALA5247616 single protein format Scientific Literature 2. ALA5250065 Binding Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based microplate reader analysis Homo sapiens 24 ALA5247616 single protein format Scientific Literature 3. ALA5250066 ADME Metabolic stability in human liver microsomes assessed as parent compound remaining preincubated for 5 mins followed by NADPH addition and measured after 30 mins by LC-MS/MS analysis Homo sapiens 9 ALA5247616 microsome format Scientific Literature 4. ALA5250067 ADME Permeability coefficient of the compound across blood brain barrier at pH 7.4 incubated for 4 hrs by PAMPA assay 10 ALA5247616 assay format Scientific Literature 5. ALA5250069 ADME C0 in rat plasma at 2 mg/kg, iv measured after 24 hrs by HPLC-UV method Rattus norvegicus 1 ALA5247616 organism-based format Scientific Literature 6. ALA5250070 ADME Cmax in rat plasma at 10 mg/kg, po measured after 24 hrs by HPLC-UV method Rattus norvegicus 1 ALA5247616 organism-based format Scientific Literature 7. ALA5250071 ADME Cmax in rat plasma at 20 mg/kg, po measured after 24 hrs by HPLC-UV method Rattus norvegicus 1 ALA5247616 organism-based format Scientific Literature 8. ALA5250072 ADME Elimination half life in rat at 2 mg/kg, iv measured after 24 hrs by HPLC-UV method Rattus norvegicus 1 ALA5247616 organism-based format Scientific Literature 9. ALA5250073 ADME Elimination half life in rat at 10 mg/kg, po measured after 24 hrs by HPLC-UV method Rattus norvegicus 1 ALA5247616 organism-based format Scientific Literature 10. ALA5250074 ADME Elimination half life in rat at 20 mg/kg, po measured after 24 hrs by HPLC-UV method Rattus norvegicus 1 ALA5247616 organism-based format Scientific Literature 11. ALA5250075 ADME Tmax in rat at 10 mg/kg, po measured after 24 hrs by HPLC-UV method Rattus norvegicus 1 ALA5247616 organism-based format Scientific Literature 12. ALA5250076 ADME Tmax in rat at 20 mg/kg, po measured after 24 hrs by HPLC-UV method Rattus norvegicus 1 ALA5247616 organism-based format Scientific Literature 13. ALA5250077 ADME AUClast in rat at 2 mg/kg, iv measured after 24 hrs by HPLC-UV method Rattus norvegicus 1 ALA5247616 organism-based format Scientific Literature 14. ALA5250078 ADME AUClast in rat at 10 mg/kg, po measured after 24 hrs by HPLC-UV method Rattus norvegicus 1 ALA5247616 organism-based format Scientific Literature 15. ALA5250079 ADME AUClast in rat at 20 mg/kg, po measured after 24 hrs by HPLC-UV method Rattus norvegicus 1 ALA5247616 organism-based format Scientific Literature 16. ALA5250080 ADME Elimination rate constant in rat at 2 mg/kg, iv measured after 24 hrs by HPLC-UV method Rattus norvegicus 1 ALA5247616 organism-based format Scientific Literature 17. ALA5250081 ADME Elimination rate constant in rat at 10 mg/kg, po measured after 24 hrs by HPLC-UV method Rattus norvegicus 1 ALA5247616 organism-based format Scientific Literature 18. ALA5250082 ADME Elimination rate constant in rat at 20 mg/kg, po measured after 24 hrs by HPLC-UV method Rattus norvegicus 1 ALA5247616 organism-based format Scientific Literature 19. ALA5250083 ADME Volume of distribution in rat at 2 mg/kg, iv measured after 24 hrs by HPLC-UV method Rattus norvegicus 1 ALA5247616 organism-based format Scientific Literature 20. ALA5250084 ADME Apparent volume of distribution in rat at 10 mg/kg, po measured after 24 hrs by HPLC-UV method Rattus norvegicus 1 ALA5247616 organism-based format Scientific Literature