| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5265491 | B | Inhibition of human TRPM8 expressed in HEK293 cells assessed as reduction in ethyl 4-methoxy-2-phenylthiazole-5-carboxylate induced Ca2+ efflux preincubated for 5 mins followed by ethyl 4-methoxy-2-phenylthiazole-5-carboxylate addition and measured for 3 mins by FLIPR assay | Homo sapiens | 60 | cell-based format | Scientific Literature | ||
| 2. | ALA5265494 | P | Dissociation constant, pKa of the compound | 11 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA5265495 | P | Lipophilicity, logD of the compound at pH 7.4 | 11 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA5265496 | A | Metabolic stability in rat liver microsomes assessed as phase 1 metabolism by measuring half life | Rattus norvegicus | 7 | microsome format | Scientific Literature | ||
| 5. | ALA5265497 | A | Metabolic stability in rat liver microsomes assessed as phase 2 metabolism by measuring half life | Rattus norvegicus | 7 | microsome format | Scientific Literature |
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