# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5250395 | B | Protac activity at CRBN/BCR-ABL in human K562 cells assessed as increase in BCR-ABL degradation incubated for 16 hrs by Western blotting analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
2. | ALA5250396 | B | Protac activity at CRBN/BCR-ABL in human K562 cells assessed as increase in c-ABL degradation incubated for 16 hrs by Western blotting analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
3. | ALA5250398 | B | Inhibition of BCR-ABL phosphorylation at Tyr245 residue in human K562 cells at 0.3 to 100 nM incubated for 16 hrs by Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA5250399 | B | Inhibition of STAT5 phosphorylation at Tyr694 residue in human K562 cells at 0.3 to 100 nM incubated for 16 hrs by Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA5250400 | B | Inhibition of CRKL phosphorylation at Tyr207 residue in human K562 cells at 0.3 to 100 nM incubated for 16 hrs by Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA5250416 | B | Protac activity at CRBN/BCR-ABL in human K562 cells assessed as increase in BCR-ABL degradation at 100 nM incubated for 6 hrs followed by compound washout measured upto 96 hrs by Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA5250417 | B | Inhibition of BCR-ABL phosphorylation at Tyr245 residue in human K562 cells at 100 nM incubated for 6 hrs followed by compound washout measured upto 96 hrs by Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA5250418 | B | Inhibition of STAT5 phosphorylation at Tyr694 residue in human K562 cells at 100 nM incubated for 6 hrs followed by compound washout measured upto 96 hrs by Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA5250419 | B | Inhibition of CRKL phosphorylation at Tyr207 residue in human K562 cells at 100 nM incubated for 6 hrs followed by compound washout measured upto 96 hrs by Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |