| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5225583 | B | Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 microsomal preparation using PGH2 as substrate assessed as inhibition of PGE2 synthesis by measuring residual activity at 10 uM preincubated for 15 mins followed by substrate addition and measured after 1 min by RP-HPLC analysis relative to control | Homo sapiens | 9 | ALA5223158 | microsome format | Scientific Literature | |
| 2. | ALA5225584 | B | Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 microsomal preparation using PGH2 as substrate assessed as inhibition of PGE2 synthesis preincubated for 15 mins followed by substrate addition and measured after 1 min by RP-HPLC analysis | Homo sapiens | 9 | ALA5223158 | microsome format | Scientific Literature | |
| 3. | ALA5225593 | F | Inhibition of 5-LO product formation in Staphylococcus aureus activated human monocyte derived macrophages at 10 uM preincubated for 15 mins followed by Staphylococcus aureus activation for 90 mins by UPLC-MS/MS analysis | Homo sapiens | 5 | ALA5223158 | cell-based format | Scientific Literature |
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