# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5225879 | Toxicity | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Mus musculus | 18 | ALA5223173 | cell-based format | Scientific Literature | |
2. | ALA5225880 | Functional | Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-1beta level incubated for 48 hrs by ELISA assay | Mus musculus | 18 | ALA5223173 | cell-based format | Scientific Literature | |
3. | ALA5225881 | Toxicity | Selectivity index, ratio of CC50 for cytotoxicity against mouse RAW264.7 cells to IC50 for antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-1beta level | 18 | ALA5223173 | cell-based format | Scientific Literature | ||
4. | ALA5225882 | Toxicity | Cytotoxicity against BALB/c mouse bone-marrow derived macrophage cells assessed as reduction in cell viability incubated for 11 days by MTT assay | Mus musculus | 8 | ALA5223173 | cell-based format | Scientific Literature | |
5. | ALA5225883 | Functional | Anti-osteoclastogensis activity in BALB/c mouse bone marrow macrophage cells assessed as inhibition of RANKL/M-CSF-induced osteoclastogenesis by measuring osteoclasts number incubated for 11 days by TRAP staining based assay | Mus musculus | 8 | ALA5223173 | cell-based format | Scientific Literature | |
6. | ALA5225884 | Toxicity | Selectivity index, ratio of CC50 for cytotoxicity against BALB/c mouse bone-marrow derived macrophage cells to IC50 for anti-osteoclastogensis activity in BALB/c mouse bone marrow macrophage cells assessed as inhibition of RANKL/M-CSF-induced osteoclastogenesis | 8 | ALA5223173 | cell-based format | Scientific Literature |