# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5236502 | T | Cytotoxicity against mouse J774.A1 cells assessed as cell viability at 10 uM incubated for 24 hrs by MTT assay (Rvb = 100%) | Mus musculus | 31 | ALA5233289 | cell-based format | Scientific Literature | |
2. | ALA5236503 | T | Cytotoxicity against mouse J774.A1 cells assessed as cell viability at 20 uM incubated for 24 hrs by MTT assay (Rvb = 100%) | Mus musculus | 31 | ALA5233289 | cell-based format | Scientific Literature | |
3. | ALA5236504 | T | Cytotoxicity against rat H9c2 cells assessed as cell viability at 10 uM incubated for 24 hrs by MTT assay (Rvb = 100%) | Rattus norvegicus | 31 | ALA5233289 | cell-based format | Scientific Literature | |
4. | ALA5236505 | T | Cytotoxicity against rat H9c2 cells assessed as cell viability at 20 uM incubated for 24 hrs by MTT assay (Rvb = 100%) | Rattus norvegicus | 31 | ALA5233289 | cell-based format | Scientific Literature | |
5. | ALA5236506 | F | Cardioprotective activity against rat H9c2 cells assessed as reduction in doxorubicin-induced cardiotoxicity by measuring cell viability at 20 uM incubated for 24 hrs in presence of doxorubicin by MTT assay | Rattus norvegicus | 6 | ALA5233289 | cell-based format | Scientific Literature | |
6. | ALA5236507 | T | Antagonizing activity against doxorubicin-induced antitumor activity in human MCF7 cells assessed as cell viability at 20 uM incubated for 24 hrs in presence of doxorubicin by MTT assay | Homo sapiens | 6 | ALA5233289 | cell-based format | Scientific Literature | |
7. | ALA5236508 | T | Induction of oxidative stress in rat H9c2 cells assessed as increase in intracellular ROS level at 20 uM incubated for 24 hrs by DCFH-DA staining based fluorometric analysis | Rattus norvegicus | 5 | ALA5233289 | cell-based format | Scientific Literature | |
8. | ALA5236509 | F | Antioxidant activity against rat H9c2 cells assessed as reduction in H2O2-induced oxidative stress by measuring reduction in intracellular ROS level at 20 uM incubated for 24 hrs by DCFH-DA staining based fluorometric analysis | Rattus norvegicus | 5 | ALA5233289 | cell-based format | Scientific Literature | |
9. | ALA5236511 | B | Inhibition of doxorubicin-induced ERK1/2 activation in rat H9c2 cells assessed as reduction in ERK1/2 phosphorylation at 20 uM in presence of doxorubicin by immunoblot analysis | Rattus norvegicus | 5 | ALA5233289 | cell-based format | Scientific Literature | |
10. | ALA5236512 | B | Activation of Akt in rat H9c2 cells assessed as increase in Akt phosphorylation at 20 uM in presence of doxorubicin by immunoblot analysis | Rattus norvegicus | 5 | ALA5233289 | cell-based format | Scientific Literature | |
11. | ALA5236513 | F | Cardioprotective activity against doxorubicin-treated rat H9c2 cells assessed as decrease in Bax protein expression at 20 uM in presence of doxorubicin by immunoblot analysis | Rattus norvegicus | 5 | ALA5233289 | cell-based format | Scientific Literature | |
12. | ALA5236514 | F | Cardioprotective activity against doxorubicin-treated rat H9c2 cells assessed as increase in Bcl2 protein expression at 20 uM in presence of doxorubicin by immunoblot analysis | Rattus norvegicus | 5 | ALA5233289 | cell-based format | Scientific Literature |