# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5236162 | B | Agonist activity at FXR in HEK293 cells assessed as maximum efficacy relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA5236163 | B | Agonist activity at FXR in HEK293 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA5236165 | A | AUC(0 to 24 hrs) in Sprague-Dawley rat liver at 5 mg/kg, po measured up to 24 hrs by LC-MS-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
4. | ALA5236166 | A | AUC(0 to 24 hrs) in Sprague-Dawley rat serum at 5 mg/kg, po measured up to 24 hrs by LC-MS-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
5. | ALA5236167 | A | Cmax in Sprague-Dawley rat liver at 5 mg/kg, po measured up to 24 hrs by LC-MS-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
6. | ALA5236168 | A | Cmax in Sprague-Dawley rat serum at 5 mg/kg, po measured up to 24 hrs by LC-MS-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
7. | ALA5236169 | A | AUC(0 to 24 hrs) in Sprague-Dawley rat serum at 1 mg/kg, iv measured up to 24 hrs by LC-MS-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
8. | ALA5236170 | A | Cmax in Sprague-Dawley rat serum at 1 mg/kg, iv measured up to 24 hrs by LC-MS-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
9. | ALA5236171 | B | Agonist activity at FXR in HEK293T cells by steady-glo luciferase assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
10. | ALA5236172 | B | Agonist activity at FXR in HEK293T cells assessed as maximum efficacy by steady-glo luciferase assay relative to control | Homo sapiens | 9 | cell-based format | Scientific Literature |