# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5242924 | B | Inhibition of tubulin polymerization (unknown origin) at 10 uM by turbidimetric analysis | Homo sapiens | 12 | ALA5241106 | protein complex format | Scientific Literature | |
2. | ALA5242925 | B | Inhibition of PARP1 (unknown origin) using [3H]NAD+ as substrate at 10 uM incubated for 15 mins by scintillation counting analysis | Homo sapiens | 12 | ALA5241106 | single protein format | Scientific Literature | |
3. | ALA5242926 | B | Inhibition of tubulin polymerization (unknown origin) by turbidimetric analysis | Homo sapiens | 3 | ALA5241106 | protein complex format | Scientific Literature | |
4. | ALA5242927 | B | Inhibition of PARP1 (unknown origin) using [3H]NAD+ as substrate incubated for 15 mins by scintillation counting analysis | Homo sapiens | 3 | ALA5241106 | single protein format | Scientific Literature | |
5. | ALA5242928 | B | Inhibition of [3H]colchicine binding to tubulin to bovine brain tubulin at 5 to 50 uM by competitive binding assay | Bos taurus | 1 | ALA5241106 | tissue-based format | Scientific Literature | |
6. | ALA5242929 | B | Inhibition of PIM-1 (unknown origin) | Homo sapiens | 1 | ALA5241106 | single protein format | Scientific Literature | |
7. | ALA5242930 | B | Inhibition of EGFR (unknown origin) | Homo sapiens | 1 | ALA5241106 | single protein format | Scientific Literature | |
8. | ALA5242931 | B | Inhibition of CDK4/Cyclin D3 (unknown origin) | Homo sapiens | 1 | ALA5241106 | protein complex format | Scientific Literature | |
9. | ALA5242932 | B | Inhibition of PI3KCG (unknown origin) | Homo sapiens | 1 | ALA5241106 | single protein format | Scientific Literature | |
10. | ALA5242933 | B | Inhibition of tubulin polymerization in human MDA-MB-231 cells assessed as cell shrinkage, increase in nuclear disruption and microtubule dispersion at 0.5 to 2.5 uM incubated for 48 hrs by immunofluorescence assay | Homo sapiens | 1 | ALA5241106 | cell-based format | Scientific Literature | |
11. | ALA5242934 | B | Inhibition of tubulin polymerization in human MDA-MB-231 cells assessed as blurred or disappeared nucleus and destruction of normal microtubule network at 12.5 uM incubated for 48 hrs by immunofluorescence assay | Homo sapiens | 1 | ALA5241106 | cell-based format | Scientific Literature | |
12. | ALA5242935 | B | Inhibition of tubulin polymerization in human MCF-10A cells assessed as destruction of normal microtubule network at 0.5 to 12.5 uM incubated for 48 hrs by immunofluorescence assay | Homo sapiens | 1 | ALA5241106 | cell-based format | Scientific Literature | |
13. | ALA5242936 | B | Inhibition of PARP-1 in human MDA-MB-231 cells assessed as induction of double strand DNA breaks by measuring increase in gammaH2AX level at 2.5 to 12.5 uM incubated for 48 hrs by western blotting analysis | Homo sapiens | 1 | ALA5241106 | cell-based format | Scientific Literature | |
14. | ALA5242937 | F | Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 2 | ALA5241106 | cell-based format | Scientific Literature | |
15. | ALA5242938 | T | Cytotoxicity against human MCF-10A cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 2 | ALA5241106 | cell-based format | Scientific Literature | |
16. | ALA5242939 | T | Selectivity index, ratio of IC50 for cytotoxicity against human MCF-10A cells to IC50 for cytotoxicity against human MDA-MB-231 cells | 2 | ALA5241106 | cell-based format | Scientific Literature | ||
17. | ALA5242940 | F | Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 1 | ALA5241106 | cell-based format | Scientific Literature | |
18. | ALA5242941 | F | Cytotoxicity against human SK-OV-3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 1 | ALA5241106 | cell-based format | Scientific Literature | |
19. | ALA5242942 | F | Cytotoxicity against human HeLa cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 1 | ALA5241106 | cell-based format | Scientific Literature | |
20. | ALA5242943 | F | Inhibition of colony formation in human MDA-MB-231 cells measured after 10 days by crystal violet staining based analysis | Homo sapiens | 1 | ALA5241106 | cell-based format | Scientific Literature |