| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5225621 | A | AUC in cynomolgus monkey at 3 mg/kg, po and measured upto 24 hrs by LC-MS/MS analysis | Macaca fascicularis | 5 | ALA5223162 | organism-based format | Scientific Literature | |
| 2. | ALA5225622 | A | Volume of distribution at steady state in cynomolgus monkey at 1 mg/kg, iv and measured upto 24 hrs by LC-MS/MS analysis | Macaca fascicularis | 5 | ALA5223162 | organism-based format | Scientific Literature | |
| 3. | ALA5225623 | A | Half life in cynomolgus monkey at 1 mg/kg, iv and measured upto 24 hrs by LC-MS/MS analysis | Macaca fascicularis | 5 | ALA5223162 | organism-based format | Scientific Literature | |
| 4. | ALA5225624 | A | Clearance in cynomolgus monkey at 1 mg/kg, iv and measured upto 24 hrs by LC-MS/MS analysis | Macaca fascicularis | 5 | ALA5223162 | organism-based format | Scientific Literature | |
| 5. | ALA5225625 | A | AUC in Sprague-Dawley rat at 3 mg/kg, po and measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 5 | ALA5223162 | organism-based format | Scientific Literature | |
| 6. | ALA5225626 | A | Clearance in Sprague-Dawley rat at 1.5 mg/kg, iv and measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 5 | ALA5223162 | organism-based format | Scientific Literature | |
| 7. | ALA5225627 | A | Fraction unbound in human plasma by LC-MS/MS analysis | Homo sapiens | 5 | ALA5223162 | cell-free format | Scientific Literature | |
| 8. | ALA5225628 | A | Time dependent inhibition of CYP2C19 in human liver microsomes using S mephenytoin as substrate by LC-MS analysis | Homo sapiens | 2 | ALA5223162 | microsome format | Scientific Literature | |
| 9. | ALA5225629 | B | Inhibition of KIT (unknown origin) in presence of ATP | Homo sapiens | 4 | ALA5223162 | single protein format | Scientific Literature | |
| 10. | ALA5225630 | B | Inhibition of FLT3 (unknown origin) in presence of ATP | Homo sapiens | 4 | ALA5223162 | single protein format | Scientific Literature | |
| 11. | ALA5225631 | B | Inhibition of TrkA (unknown origin) in presence of ATP | Homo sapiens | 4 | ALA5223162 | single protein format | Scientific Literature | |
| 12. | ALA5225632 | A | Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate by LC-MS analysis | Homo sapiens | 3 | ALA5223162 | microsome format | Scientific Literature | |
| 13. | ALA5225633 | A | Permeability across apical to basolateral side in human Caco2 cells at 50 uM and measured after 120 mins by LC-MS analysis | Homo sapiens | 8 | ALA5223162 | cell-based format | Scientific Literature | |
| 14. | ALA5225634 | B | Binding affinity to recombinant human HPK1 (1 to 346 residues) expressed sf9 cells incubated for 1 hr by LanthaScreen assay | Homo sapiens | 18 | ALA5223162 | cell-based format | Scientific Literature | |
| 15. | ALA5225635 | B | Inhibition of human HPK1 in human Jurkat cells assessed as reduction in SLP76 phosphorylation incubated for 1 hr by HTRF assay | Homo sapiens | 14 | ALA5223162 | cell-based format | Scientific Literature | |
| 16. | ALA5225636 | A | Intrinsic clearance in human liver microsomes at 1 uM and measured upto 30 mins in presence of NADPH by LC-MS analysis | Homo sapiens | 13 | ALA5223162 | microsome format | Scientific Literature | |
| 17. | ALA5225637 | A | Oral bioavailability in cynomolgus monkey at 3 mg/kg and measured upto 24 hrs by LC-MS/MS analysis | Macaca fascicularis | 5 | ALA5223162 | organism-based format | Scientific Literature | |
| 18. | ALA5225644 | A | Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate by LC-MS analysis | Homo sapiens | 4 | ALA5223162 | microsome format | Scientific Literature |
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