| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5264781 | F | Cytotoxicity against human SK-MEL3 cells assessed as cell growth inhibition upto 10 uM measured after 48 hrs by Caspase-Glo reagent based assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 2. | ALA5264792 | F | Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition upto 10 uM measured after 48 hrs by Caspase-Glo reagent based assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 3. | ALA5264794 | F | Cytotoxicity against human A498 cells assessed as cell growth inhibition upto 10 uM measured after 48 hrs by Caspase-Glo reagent based assay | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
| 4. | ALA5264795 | F | Cytotoxicity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by Caspase-Glo reagent based assay | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
| 5. | ALA5264796 | F | Cytotoxicity against human IMR-90 cells assessed as cell growth inhibition upto 10 uM measured after 48 hrs by Caspase-Glo reagent based assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 6. | ALA5264797 | B | Inhibition of human N-terminal His-GST-tagged recombinant PDE3A (669-end residues) using fluorescent labelled cAMP as substrate | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 7. | ALA5264798 | B | Inhibition of human recombinant PDE3B | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 8. | ALA5264799 | U | Selectivity ratio, ratio of IC50 for human PDE3A to EC50 for cytotoxicity against human HeLa cells | 7 | cell-based format | Scientific Literature | |||
| 9. | ALA5264800 | U | Selectivity ratio, ratio of IC50 for human PDE3B to EC50 for cytotoxicity against human HeLa cells | 7 | cell-based format | Scientific Literature | |||
| 10. | ALA5264802 | A | Microsomal stability in human liver microsomes assessed as parent compound remaining measured after 1 hr in presence of NADPH by UHPLC-MS analysis | Homo sapiens | 7 | microsome format | Scientific Literature | ||
| 11. | ALA5264803 | A | Microsomal stability in mouse liver microsomes assessed as parent compound remaining at 1 uM measured after 1 hr in presence of NADPH by UHPLC-MS analysis | Mus musculus | 7 | microsome format | Scientific Literature | ||
| 12. | ALA5264804 | A | Plasma protein binding in human incubated for 5 hrs by UPLC-MS method | Homo sapiens | 7 | cell-free format | Scientific Literature | ||
| 13. | ALA5264805 | A | Plasma protein binding in mouse incubated for 5 hrs by UPLC-MS method | Mus musculus | 7 | cell-free format | Scientific Literature | ||
| 14. | ALA5264806 | A | Stability in human plasma assessed as parent compound remaining after 5 hrs | Homo sapiens | 7 | cell-free format | Scientific Literature | ||
| 15. | ALA5264807 | A | Stability in mouse plasma assessed as parent compound remaining after 5 hrs | Mus musculus | 7 | cell-free format | Scientific Literature |
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