# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5240518 | F | Antiproliferative activity against human MM1.S cells assessed as inhibition of cell growth incubated for 72 hrs MTS assay | Homo sapiens | 12 | ALA5236646 | cell-based format | Scientific Literature | |
2. | ALA5240519 | F | Antiproliferative activity against human MM4-11 cells assessed as inhibition of cell growth incubated for 72 hrs MTS assay | Homo sapiens | 12 | ALA5236646 | cell-based format | Scientific Literature | |
3. | ALA5240528 | B | Protac activity at CRBN/BRD4 in human MM1.S cells assessed as induction of BRD4 protein degradation by measuring residual activity at 0.2 uM incubated for 3 hrs by Western blot analysis relative to control | Homo sapiens | 3 | ALA5236646 | cell-based format | Scientific Literature | |
4. | ALA5240529 | B | Protac activity at CRBN/BRD4 in human MM1.S cells assessed as induction of BRD4 protein degradation by measuring residual activity at 0.6 uM incubated for 3 hrs by Western blot analysis relative to control | Homo sapiens | 3 | ALA5236646 | cell-based format | Scientific Literature | |
5. | ALA5240536 | B | Protac activity at CRBN/BRD4 in human MM1.S cells assessed as induction of BRD4 protein degradation by measuring residual activity at 1.8 uM incubated for 3 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5236646 | cell-based format | Scientific Literature | |
6. | ALA5240554 | B | Protac activity at CRBN/BRD4 in human MV4-11 cells assessed as induction of BRD4 protein degradation by measuring residual activity at 0.04 uM incubated for 3 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5236646 | cell-based format | Scientific Literature | |
7. | ALA5240555 | B | Protac activity at CRBN/BRD4 in human MV4-11 cells assessed as induction of BRD4 protein degradation by measuring residual activity at 0.12 uM incubated for 3 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5236646 | cell-based format | Scientific Literature | |
8. | ALA5240556 | B | Protac activity at CRBN/BRD4 in human MV4-11 cells assessed as induction of BRD4 protein degradation by measuring residual activity at 0.36 uM incubated for 3 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5236646 | cell-based format | Scientific Literature |