# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5236394 | B | Binding affinity to BRD4-BD1 (unknown origin) assessed as change in melting temperature at 200 uM incubated for 30 to 60 mins by SYPRO orange dye based thermal shift assay | Homo sapiens | 26 | ALA5233284 | single protein format | Scientific Literature | |
2. | ALA5236395 | B | Inhibition of BRD4-BD1 (unknown origin) using C-terminal biotinylated tetra-acetylated histone H4 peptide as substrate at 20 uM incubated for 2.5 hrs by alphascreen assay relative to control | Homo sapiens | 26 | ALA5233284 | single protein format | Scientific Literature | |
3. | ALA5236396 | B | Inhibition of BRD4-BD1 (unknown origin) using C-terminal biotinylated tetra-acetylated histone H4 peptide as substrate incubated for 2.5 hrs by alphascreen assay | Homo sapiens | 26 | ALA5233284 | single protein format | Scientific Literature | |
4. | ALA5236397 | F | Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth at 10 uM incubated for 96 to 120 hrs by celltiter glo assay relative to control | Homo sapiens | 26 | ALA5233284 | cell-based format | Scientific Literature | |
5. | ALA5236398 | F | Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth incubated for 96 to 120 hrs by celltiter glo assay | Homo sapiens | 26 | ALA5233284 | cell-based format | Scientific Literature | |
6. | ALA5236399 | F | Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell growth at 10 uM incubated for 96 to 120 hrs by celltiter glo assay relative to control | Homo sapiens | 26 | ALA5233284 | cell-based format | Scientific Literature | |
7. | ALA5236400 | F | Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell growth incubated for 96 to 120 hrs by celltiter glo assay | Homo sapiens | 26 | ALA5233284 | cell-based format | Scientific Literature | |
8. | ALA5236401 | B | Binding affinity to BRD2 BD1 (unknown origin) assessed as change in melting temperature at 200 uM incubated for 30 to 60 mins by SYPRO orange dye based thermal shift assay | Homo sapiens | 2 | ALA5233284 | single protein format | Scientific Literature | |
9. | ALA5236402 | B | Binding affinity to BRD3 BD1 (unknown origin) assessed as change in melting temperature at 200 uM incubated for 30 to 60 mins by SYPRO orange dye based thermal shift assay | Homo sapiens | 2 | ALA5233284 | single protein format | Scientific Literature | |
10. | ALA5236403 | B | Binding affinity to CBP (unknown origin) assessed as change in melting temperature at 200 uM incubated for 30 to 60 mins by SYPRO orange dye based thermal shift assay | Homo sapiens | 2 | ALA5233284 | single protein format | Scientific Literature | |
11. | ALA5236404 | B | Binding affinity to EP300 (unknown origin) assessed as change in melting temperature at 200 uM incubated for 30 to 60 mins by SYPRO orange dye based thermal shift assay | Homo sapiens | 2 | ALA5233284 | single protein format | Scientific Literature | |
12. | ALA5236405 | B | Binding affinity to CECR2 (unknown origin) assessed as change in melting temperature at 200 uM incubated for 30 to 60 mins by SYPRO orange dye based thermal shift assay | Homo sapiens | 2 | ALA5233284 | single protein format | Scientific Literature | |
13. | ALA5236406 | B | Binding affinity to BAZ2B (unknown origin) assessed as change in melting temperature at 200 uM incubated for 30 to 60 mins by SYPRO orange dye based thermal shift assay | Homo sapiens | 2 | ALA5233284 | single protein format | Scientific Literature | |
14. | ALA5236407 | B | Binding affinity to PCAF (unknown origin) assessed as change in melting temperature at 200 uM incubated for 30 to 60 mins by SYPRO orange dye based thermal shift assay | Homo sapiens | 2 | ALA5233284 | single protein format | Scientific Literature | |
15. | ALA5236408 | B | Binding affinity to SMARCA2A (unknown origin) assessed as change in melting temperature at 200 uM incubated for 30 to 60 mins by SYPRO orange dye based thermal shift assay | Homo sapiens | 2 | ALA5233284 | single protein format | Scientific Literature | |
16. | ALA5236409 | B | Inhibition of BRD4 BD1 in human MV4-11 cells assessed as inhibition of c-myc protein expression at 20 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA5233284 | cell-based format | Scientific Literature |