# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5240319 | B | Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs by fluorescence polarization assay | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
2. | ALA5240320 | B | Binding affinity to HSP90beta (unknown origin) | Homo sapiens | 42 | single protein format | Scientific Literature | ||
3. | ALA5240321 | B | Selectivity index, ratio of IC50 for binding affinity to HSP90beta (unknown origin) to IC50 for binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
4. | ALA5240322 | B | Binding affinity to Grp94 (unknown origin) incubated for 24 hrs by fluorescence polarization assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
5. | ALA5240323 | B | Binding affinity to Trap1 (unknown origin) incubated for 24 hrs by fluorescence polarization assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
6. | ALA5240324 | B | Selectivity index, ratio of IC50 for binding affinity to Grp94 (unknown origin) to IC50 for binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
7. | ALA5240325 | B | Selectivity index, ratio of IC50 for binding affinity to Trap1 (unknown origin) to IC50 for binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
8. | ALA5240326 | F | Antiproliferative activity against human NCI-H522 cell assessed as inhibition of cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
9. | ALA5240327 | F | Antiproliferative activity against human SK-OV-3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
10. | ALA5240328 | F | Antiproliferative activity against human UO-31 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
11. | ALA5240329 | B | Inhibition of HSP90alpha in human NCI-H522 cells assessed as decrease in Her2 protein level incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA5240330 | B | Inhibition of HSP90alpha in human NCI-H522 cells assessed as decrease in Raf-1 protein level incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA5240331 | B | Inhibition of HSP90alpha in human NCI-H522 cells assessed as decrease in Akt protein level incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA5240332 | B | Inhibition of HSP90alpha in human NCI-H522 cells assessed as decrease in survivin protein level incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA5240333 | B | Inhibition of HSP90alpha in human NCI-H522 cells assessed as decrease in c-Src protein level incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA5240334 | B | Inhibition of HSP90alpha in human SK-OV-3 cells assessed as decrease in Her2 protein level incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA5240335 | B | Inhibition of HSP90alpha in human SK-OV-3 cells assessed as decrease in Raf-1 protein level incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA5240336 | B | Inhibition of HSP90alpha in human SK-OV-3 cells assessed as decrease in Akt protein level incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA5240337 | B | Inhibition of HSP90alpha in human SK-OV-3 cells assessed as decrease in survivin protein level incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA5240338 | B | Inhibition of HSP90alpha in human SK-OV-3 cells assessed as decrease in c-Src protein level incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |