| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5225666 | B | Agonist activity at human SST2 receptor expressed in CHO-K1 cells assessed as inhibition of NKH477-induced intracellular cAMP accumulation incubated for 20 mins by HTRF assay | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 2. | ALA5225667 | B | Agonist activity at human SST1 receptor expressed in CHO-K1 cells assessed as inhibition of NKH477-induced intracellular cAMP accumulation incubated for 20 mins by HTRF assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 3. | ALA5225668 | B | Agonist activity at human SST3 receptor expressed in CHO-K1 cells assessed as inhibition of NKH477-induced intracellular cAMP accumulation incubated for 20 mins by HTRF assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 4. | ALA5225669 | B | Agonist activity at human SST4 receptor expressed in CHO-K1 cells assessed as inhibition of NKH477-induced intracellular cAMP accumulation incubated for 20 mins by HTRF assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 5. | ALA5225670 | B | Agonist activity at human SST5 receptor expressed in CHO-K1 cells assessed as inhibition of NKH477-induced intracellular cAMP accumulation incubated for 20 mins by HTRF assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 6. | ALA5225671 | B | Selectivity index, ratio of pEC50 for agonist activity at human SST1 receptor expressed in CHO-K1 cells to pEC50 for agonist activity at human SST2 receptor expressed in CHO-K1 cells | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 7. | ALA5225672 | B | Selectivity index, ratio of pEC50 for agonist activity at human SST3 receptor expressed in CHO-K1 cells to pEC50 for agonist activity at human SST2 receptor expressed in CHO-K1 cells | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 8. | ALA5225673 | B | Selectivity index, ratio of pEC50 for agonist activity at human SST4 receptor expressed in CHO-K1 cells to pEC50 for agonist activity at human SST2 receptor expressed in CHO-K1 cells | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 9. | ALA5225674 | B | Selectivity index, ratio of pEC50 for agonist activity at human SST5 receptor expressed in CHO-K1 cells to pEC50 for agonist activity at human SST2 receptor expressed in CHO-K1 cells | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 10. | ALA5225676 | A | Half life in human liver microsomes | Homo sapiens | 5 | microsome format | Scientific Literature | ||
| 11. | ALA5225677 | A | Half life in rat liver microsomes | Rattus norvegicus | 5 | microsome format | Scientific Literature | ||
| 12. | ALA5225678 | T | Inhibition of hERG by patch clamp assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA5225679 | A | Inhibition of human CYP2C9 expressed in insect cell microsomes in presence of NADP+ by fluorescence based analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 14. | ALA5225680 | A | Inhibition of human CYP2C19 expressed in insect cell microsomes in presence of NADP+ by fluorescence based analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 15. | ALA5225681 | A | Inhibition of human CYP2D6 expressed in insect cell microsomes in presence of NADP+ by fluorescence based analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 16. | ALA5225682 | A | Inhibition of human CYP3A4 expressed in insect cell microsomes in presence of NADP+ by fluorescence based analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 17. | ALA5225683 | A | Inhibition of human CYP2C9 expressed in insect cell microsomes at 10 uM in presence of NADP+ by fluorescence based analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 18. | ALA5225684 | A | Inhibition of human CYP2C19 expressed in insect cell microsomes at 10 uM in presence of NADP+ by fluorescence based analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 19. | ALA5225685 | A | Inhibition of human CYP2D6 expressed in insect cell microsomes at 10 uM in presence of NADP+ by fluorescence based analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 20. | ALA5225686 | A | Inhibition of human CYP3A4 expressed in insect cell microsomes at 10 uM in presence of NADP+ by fluorescence based analysis | Homo sapiens | 2 | microsome format | Scientific Literature |
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