| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5249658 | Functional | Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay | Homo sapiens | 10 | ALA5247607 | cell-based format | Scientific Literature | |
| 2. | ALA5249659 | Toxicity | Cytotoxicity against human CCD 19Lu cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay | Homo sapiens | 10 | ALA5247607 | cell-based format | Scientific Literature | |
| 3. | ALA5249660 | Toxicity | Selectivity index, ratio of IC50 for cytotoxicity against human CCD 19Lu cells to IC50 for cytotoxicity against human A549 cells | 10 | ALA5247607 | cell-based format | Scientific Literature | ||
| 4. | ALA5249661 | Functional | Cytotoxicity against human PANC-1 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay | Homo sapiens | 10 | ALA5247607 | cell-based format | Scientific Literature | |
| 5. | ALA5249662 | Toxicity | Cytotoxicity against human hTERT-HPNE cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay | Homo sapiens | 10 | ALA5247607 | cell-based format | Scientific Literature | |
| 6. | ALA5249663 | Toxicity | Selectivity index, ratio of IC50 for cytotoxicity against human hTERT-HPNE cells to IC50 for cytotoxicity against human PANC-1 cells | 10 | ALA5247607 | cell-based format | Scientific Literature | ||
| 7. | ALA5249665 | Functional | Inhibition of DNA synthesis in human A549 cells at 1.49 uM incubated for 24 hrs by BrdU incorporation assay relative to control | Homo sapiens | 1 | ALA5247607 | cell-based format | Scientific Literature | |
| 8. | ALA5249666 | Functional | Inhibition of DNA synthesis in human A549 cells at 2.98 uM incubated for 24 hrs by BrdU incorporation assay relative to control | Homo sapiens | 1 | ALA5247607 | cell-based format | Scientific Literature | |
| 9. | ALA5249667 | Functional | Inhibition of DNA synthesis in human A549 cells at 5.96 uM incubated for 24 hrs by BrdU incorporation assay relative to control | Homo sapiens | 1 | ALA5247607 | cell-based format | Scientific Literature | |
| 10. | ALA5249674 | Functional | Inhibition of DNA synthesis in human PANC-1 cells at 5.96 uM incubated for 24 hrs by BrdU incorporation assay relative to control | Homo sapiens | 1 | ALA5247607 | cell-based format | Scientific Literature | |
| 11. | ALA5249677 | Functional | Induction of apoptosis in human A549 cells assessed as early apoptotic cells at IC50 incubated for 24 hrs by annexin V-FITC/PI staining based flow cytometry analysis (Rvb = 5.6%) | Homo sapiens | 3 | ALA5247607 | cell-based format | Scientific Literature | |
| 12. | ALA5249678 | Functional | Induction of apoptosis in human A549 cells assessed as late apoptotic cells at IC50 incubated for 24 hrs by annexin V-FITC/PI staining based flow cytometry analysis (Rvb = 6.5 %) | Homo sapiens | 3 | ALA5247607 | cell-based format | Scientific Literature | |
| 13. | ALA5249679 | Functional | Induction of apoptosis in human A549 cells assessed as total cell viability at IC50 incubated for 24 hrs by annexin V-FITC/PI staining based flow cytometry analysis (Rvb = 85.6 %) | Homo sapiens | 3 | ALA5247607 | cell-based format | Scientific Literature | |
| 14. | ALA5249681 | Functional | Induction of apoptosis in human PANC-1 cells assessed as early apoptotic cells at IC50 incubated for 24 hrs by annexin V-FITC/PI staining based flow cytometry analysis (Rvb = 0%) | Homo sapiens | 5 | ALA5247607 | cell-based format | Scientific Literature | |
| 15. | ALA5249682 | Functional | Induction of apoptosis in human PANC-1 cells assessed as late apoptotic cells at IC50 incubated for 24 hrs by annexin V-FITC/PI staining based flow cytometry analysis (Rvb = 0.2%) | Homo sapiens | 5 | ALA5247607 | cell-based format | Scientific Literature | |
| 16. | ALA5249683 | Functional | Induction of apoptosis in human PANC-1 cells assessed as total cell viability at IC50 incubated for 24 hrs by annexin V-FITC/PI staining based flow cytometry analysis (Rvb = 84.4%) | Homo sapiens | 5 | ALA5247607 | cell-based format | Scientific Literature | |
| 17. | ALA5249685 | Functional | Induction of apoptosis in human A549 cells assessed as activation of caspase-3 by measuring caspase-3 positive cells at IC50 incubated for 24 hrs by flow cytometry analysis (Rvb = 8.4%) | Homo sapiens | 3 | ALA5247607 | cell-based format | Scientific Literature | |
| 18. | ALA5249686 | Functional | Induction of apoptosis in human A549 cells assessed as activation of caspase-3 by measuring caspase-3 negative cells at IC50 incubated for 24 hrs by flow cytometry analysis (Rvb = 91.1%) | Homo sapiens | 3 | ALA5247607 | cell-based format | Scientific Literature | |
| 19. | ALA5249687 | Functional | Induction of apoptosis in human PANC-1 cells assessed as activation of caspase-3 by measuring caspase-3 positive cells at IC50 incubated for 24 hrs by flow cytometry analysis (Rvb = 1.8%) | Homo sapiens | 5 | ALA5247607 | cell-based format | Scientific Literature | |
| 20. | ALA5249688 | Functional | Induction of apoptosis in human PANC-1 cells assessed as activation of caspase-3 by measuring caspase-3 negative cells at IC50 incubated for 24 hrs by flow cytometry analysis (Rvb = 98.5 %) | Homo sapiens | 5 | ALA5247607 | cell-based format | Scientific Literature |
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