| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5239655 | B | Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured after 90 mins by TR-FRET assay | Homo sapiens | 17 | single protein format | Scientific Literature | ||
| 2. | ALA5239656 | B | Inhibition of GST20-tagged LRRK2 in human SH-SY5Y cells assessed as reduction in pSer935 phosphorylation incubated for 90 mins by MSD assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 3. | ALA5239657 | A | Efflux ratio of apparent permeability from basal to apical over apical to basolateral side in rat P-gp transfected LLC-PK1 cells | Sus scrofa | 15 | cell-based format | Scientific Literature | ||
| 4. | ALA5239658 | A | Apparent permeability in rat P-gp transfected LLC-PK1 cells at 0.1 to 1 uM incubated 3 hrs by LC-MS/MS analysis | Sus scrofa | 15 | cell-based format | Scientific Literature | ||
| 5. | ALA5239669 | A | Clearance in rat at 0.1 mg/kg, iv administered as cassette dose measured upto 24 hrs by LC-MS/MS method | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 6. | ALA5239670 | A | Unbound clearance in rat at 0.1 mg/kg, iv administered as cassette dose measured upto 24 hrs by LC-MS/MS method | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 7. | ALA5239671 | A | Mean residence time in rat at 0.1 mg/kg, iv administered as cassette dose measured upto 24 hrs by LC-MS/MS method | Rattus norvegicus | 3 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!