# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5255021 | B | Binding affinity to human alpha-syn expressed in Escherichia coli BL21 (DE3) cells assessed as protein-compound complex formation at 100 uM incubated for 3 hrs by ESI-MS spectrum analysis | Homo sapiens | 16 | ALA5252574 | cell-based format | Scientific Literature | |
2. | ALA5255022 | B | Inhibition of human alpha-syn expressed in Escherichia coli BL21 (DE3) cells aggregation at 80 uM incubated at compound:protein ratio of 1:1 for 36 hrs by ThT dye based fluorescence assay relative to control | Homo sapiens | 6 | ALA5252574 | cell-based format | Scientific Literature | |
3. | ALA5255023 | B | Inhibition of human alpha-syn expressed in Escherichia coli BL21 (DE3) cells aggregation at 400 uM incubated at compound:protein ratio of 5:1 for 36 hrs by ThT dye based fluorescence assay relative to control | Homo sapiens | 7 | ALA5252574 | cell-based format | Scientific Literature |