# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5252492 | B | Inhibition of JAK1/TYK2 in human M07E cells assessed as reduction of IFN alpha stimulated STAT phosphorylation preincubated for 30 mins followed by IFN alpha stimulation for 15 mins by flow cytometry method | Homo sapiens | 8 | ALA5247683 | cell-based format | Scientific Literature | |
2. | ALA5252493 | B | Inhibition of JAK1/JAK3 in human blood assessed as reduction of IL-2 stimulated STAT phosphorylation preincubated for 30 mins followed by IL-2 stimulation for 15 mins by flow cytometry method | Homo sapiens | 8 | ALA5247683 | tissue-based format | Scientific Literature | |
3. | ALA5252495 | B | Inhibition of GST-fused JAK1 (866 to 1154 residues) (unknown origin) using FITC-AhxKKSRGDYMTMQIG-NH2 peptide as substrate incubated for 60 mins in presence of ATP by Janus kinase assay | Homo sapiens | 5 | ALA5247683 | single protein format | Scientific Literature | |
4. | ALA5252496 | B | Inhibition of GST-fused JAK2 (808 to 1132 residues) (unknown origin) using Carboxyfluorescein-Ahx-GGEEEEYFELVKKKK peptide as substrate incubated for 60 mins in presence of ATP by Janus kinase assay | Homo sapiens | 5 | ALA5247683 | single protein format | Scientific Literature | |
5. | ALA5252497 | B | Inhibition of GST-fused JAK3 (811 to 1124 residues) (unknown origin) using Carboxyfluorescein-Ahx-GGEEEEYFELVKKKK peptide as substrate incubated for 60 mins in presence of ATP by Janus kinase assay | Homo sapiens | 5 | ALA5247683 | single protein format | Scientific Literature | |
6. | ALA5252498 | B | Inhibition of GST-fused Tyk2 (888 to 1187 residues) (unknown origin) using FITC-AhxKKSRGDYMTMQIG-NH2 peptide as substrate incubated for 60 mins in presence of ATP by Janus kinase assay | Homo sapiens | 5 | ALA5247683 | single protein format | Scientific Literature | |
7. | ALA5252499 | B | Inhibition of JAK1/JAK3 in human M07E cells assessed as reduction of IL-15 stimulated STAT phosphorylation preincubated for 30 mins followed by IL-15 stimulation for 15 mins by flow cytometry method | Homo sapiens | 5 | ALA5247683 | cell-based format | Scientific Literature |